Authors: I. Crha; P. Ventruba; M. Petrenko; H. Višňová Authors‘ workplace: I. gynek. -porod. klinika LF MU, Brno, přednosta prof. MUDr. P. Ventruba, DrSc. Published in: Ceska Gynekol 1999; (4): 230-234 Category:
The study reviews recent developments with regard to postsurgical adhesion formation, the roleof some cytokines and possible prevention. Interleukin-1beta (IL-1 beta) levels in peritoneal fluidwere assayed during 24 and 48 hours after laparoscopic or laparotomic surgery and the influenceof diclofenac was evaluated. IL-1beta levels in peritoneal fluid were substantially lower afterlaparoscopic adnexal surgery than after laparotomy. Application of diclofenac after abdominalhysterectomies reduced substantially intraperitoneal IL-1beta levels.
Key words: peritoneal adhesions, interleukin-1beta, laparoscopy
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