Early extraction of the first permanent molar and spontaneous closure of the extraction gap – indications, risks and implications
Authors:
E. Řezáčová 1,2,*; J. Hálek 1,3
Authors‘ workplace:
Korespondující autorka
*; Stomatologická klinika, Lékařská fakulta v Plzni, Univerzita Karlova
1; Stomatologická klinika, Fakultní nemocnice Plzeň
2; Ortodontická ordinace Rideto, s. r. o., privátní praxe, Strakonice
3
Published in:
Česká stomatologie / Praktické zubní lékařství, ročník 125, 2025, 3, s. 63-69
Category:
Review Article
Overview
Introduction and aim: Severe caries, malformation or other damage to the first permanent molar can be treated by extraction in clinical practice. This consideration is based on the assumption that extraction of the first permanent molar will result in spontaneous mesial displacement of the second permanent molar and its repositioning in place of the first molar, thereby closing the gap. However, daily clinical practice shows that this procedure is not so clear-cut and yields different results. The aim of this paper is to summarize the literature findings related to the extraction of the first permanent molar and the subsequent spontaneous closure of the extraction gap, as well as to review the recommended clinical procedures.
Methods: PubMed, ResearchGate and Google Scholar databases were used to indentify relevant studies. Searches were conducted in English and Czech using the key words "first permanent molar", "extraction", "spontaneous" and "gap closure". Studies published between 2000 and 2024 were included in the review.
Results: Seventeen articles met the inclusion criteria. Additional articles that did not fully meet the criteria were also included to provide a more comprehensive overview of the topic. Conclusion: Extraction of the first permanent molar is a procedure with significant consequences for the development of an individual's dentition. Appropriate timing and careful indication are essential, as improper management may result in complicated or even irreversible occlusal defects. Therefore, it is always advisable to consult an orthodontist before any early extraction of a permanent tooth.
Keywords:
first permanent molar, extraction, spontaneous, gap closure
Sources
- Elhussein M, Jamal H. Molar incisor hypomineralisation – to extract or to restore beyond the optimal age? Children (Basel). 2020; 7(8): 91. doi: 10.3390/children7080091
- Patel S, Ashley P, Noar J. Radiographic prognostic factors determining spontaneous space closure after loss of the permanent first molar. Am J Orthod Dentofacial Orthop. 2017; 151(4): 718–726. doi: 10.1016/j.ajodo.2016.09.018
- Sayagh M, Maniere-Ezvan A, Vernet C, Muller-Bolla M. Therapeutic decisions in the presence of decayed permanent first molars in young subjects: a descriptive inquiry. Int Orthod. 2012; 10(3): 318–336. doi: 10.1016/j.ortho.2012.06.001
- Jälevik B.´Prevalence and diagnosis of molar-incisorhypomineralisation (MIH): A systematic review. Eur Arch Paediatr Dent. 2010; 11(2): 59–64. doi: 10.1007/BF03262714
- Hajdarević A, Čirgić E, Robertson A, Sabel N, Jälevik B. Treatment choice for first permanent molars affected with molar-incisor hypomineralization, in patients 7–8 years of age: a questionnaire study among Swedish general dentists, orthodontists, and pediatric dentists. Eur Arch Paediatr Dent. 2024; 25(1): 93–103. doi: 10.1007/s40368-023-00860-9
- Hamza B, Papageorgiou SN, Patcas R, Schätzle M. Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review and metaanalysis. Eur J Orthod. 2024; 46(6): cjae054. doi: 10.1093/ejo/cjae054
- Liu Y, Geng K, Chu Y, Xu M, Zha L. Third molar mineralization in relation to chronologic age estimation of the Han in central southern China. Int J Legal Med. 2018; 132(5): 1427–1435. doi: 10.1007/s00414-018-1804-x
- Cobourne MT, Williams A, Harrison M. National clinical guidelines for the extraction of first permanent molars in children. Br Dent J. 2014; 217(11): 643–648. doi: 10.1038/sj.bdj.2014.1053
- Salem K, Ezaani P. Radiographic evaluation of the developmental stages of second and third molars in 7 to 11-year-old children and its implication in the treatment of first molars with poor prognosis. J Res Dent Maxillofac Sci 2016; 1(4): 1–8, doi: 10.29252/jrdms.1.4.1
- Sabbagh HJ, Samara AA, Agou SH, Turkistani J, Al Malik MI, Alotaibi HA, Alsolami ASD, Bamashmous NO. Spontaneous space closure after extraction of young first permanent molar. Retrospective cohort study. Peer J. 2024; 12: e18276. doi: 10.7717/peerj.18276
- Aldahool Y, Sonesson M, Dimberg L. Spontaneous space closure in patients treated with early extraction of the first permanent molar: a retrospective cohort study using radiographs. Angle Orthod. 2024; 94(2): 180–186. doi: 10.2319/061923-423.1
- Ay S, Agar U, Biçakçi AA, Köşger HH. Changes in mandibular third molar angle and position after unilateral mandibular first molar extraction. Am J Orthod Dentofacial Orthop. 2006; 129(1): 36–41. doi: 10.1016/j.ajodo.2004.10.010
- Teo TK, Ashley PF, Parekh S, Noar J. The evaluation of spontaneous space closure after the extraction of first permanent molars. Eur Arch Paediatr Dent. 2013; 14(4): 207–212. doi: 10.1007/s40368-013-0042-7
- Ertuğrul CÇ, Özbey H, Gün AI. Early extraction of the first permanent molars: a five-year follow-up study. Eur J Paediatr Dent. 2022; 23(2): 111–115. doi: 10.23804/ejpd.2022.23.02.04
- Abu Aihaija ES, McSheny PF, Richardson A. A cephalometric study of the effect of extraction of lower first permanent molars. J Clin Pediatr Dent. 2000; 24(3): 195–198.
- Richardson A. Spontaneous changes in the incisor relationship following extraction of lower first permanent molars. Br J Orthod. 1979; 6(2): 85–90. doi: 10.1179/bjo.6.2.85
- Gill DS, Lee RT, Tredwin CJ. Treatment planning for the loss of first permanent molars. Dent Update. 2001; 28(6): 304–308. doi: 10.12968/denu.2001.28.6.304
- Normando AD, Maia FA, Ursi WJ, Simone JL. Dentoalveolar changes after unilateral extractions of mandibular first molars and their influence on third molar development and position. World J Orthod. 2010; 11(1): 55–60.
- Cağlaroğlu M, Kilic N, Erdem A. Effects of early unilateral first molar extraction on skeletal asymmetry. Am J Orthod Dentofacial Orthop. 2008; 134(2): 270–275. doi: 10.1016/j.ajodo.2006.07.036
- Koťová, M., Hovorka, J. Ztráta prvního stálého moláru u mladých pacientů. Čes. stomatol. Prakt. zub. lék. 2013; 113 : 14–19. doi: 10.51479/cspzl.2013.005
- Jälevik B, Möller M. Evaluation of spontaneous space closure and development of permanent dentition after extraction of hypomineralized permanent first molars. Int J Paediatr Dent. 2007; 17(5): 328–335. doi: 10.1111/j.1365-263X.2007.00849.x
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Maxillofacial surgery Orthodontics Dental medicineArticle was published in
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