Authors: J. Hodosy 1,2; P. Celec 1,2,3; T. Červenka 1; J. Vodrážka 4; S. Veselá 5; Tomandlová A. Božek P. 5 6; L. Halčák 7; V. Rendeková 7; Daniela Ostatníková 8; Z. Putz 9; A. Izákovičová 10 Authors‘ workplace: Lekárska fakulta, Univerzita Komenského, Bratislava 2Prírodovedecká fakulta, Univerzita Komenského, Bratislava 3Medizinische Fakultät, Georg-August Universität, Göttingen 4I. stomatologická klinika, Univerzita Komenského, Bratislava 5III. stomatologická k 1 Published in: Česká stomatologie / Praktické zubní lékařství, ročník , 2004, 2, s. 57-70 Category:
Summary: Introduction: Thiobarbituric acid reacting substances (TBARS) are products oflipoperoxidation. Lipoperoxidation damages various tissues by reactive oxygen intermediates(ROI) and thus TBARS are generally considered as markers of oxidation stress and lipidimpairment.Aim. The aim of this project was to find possible nexus between chosen characteristics ofimmune system, parodont status and TBARS concentrations in saliva in healthy volunteers.In addition, we tried to find the origin of TBARS in saliva in patients with parodontopathies,where we focused on entire or partially plasmatic TBARS passage to saliva hypothesis.Subjects & Methods. Our volunteers consisted of 31 young healthy men and 29 younghealthy women with an average age of 21.5 ± 1.4 yr (Study A) and 15 patients in age intervalof 20–60 yr (Study B). Parodont status was examined using PBI (Papillary-Bleeding-Index).TBARS were determined, in plasma and saliva, spectrofluorometrically (λex = 515 nm, λem =553 nm). Testosterone (TST) levels were measured using radioimmunoassay. Immunoglobulinesand other haematological parametres were determined turbidimetrically.Results. Study A. The women with higher PBI levels had shown higher concentrations ofTST (p
Key words: TBARS – malondialdehyde – salivary testosterone – PBI – parodontopathies –oxidation stress
Don‘t have an account? Create new account
Enter the email address that you registered with. We will send you instructions on how to set a new password.
