Authors: E. Češková Authors‘ workplace: Psychiatrická klinika LF MU, Brno, přednosta prof. MUDr. E. Češková, CSc. Published in: Čes. a slov. Psychiat., , 1999, No. 7, pp. 443-452. Category:
The author reviews knew knowledge about bipolar disorder, including histo-ry, epidemiology, prognosis and economic aspects. The treatment is summa-rized in more details. The advantages and disadvantages of classicaltreatment of bipolar disorder and those of new anticonvulsants, e.g. lamotri-gine, gabapentine and topiramate are compared. Further own results concer-ning efficacy of lamotrigine in patients with depressive disorder arepresented. The more advantageous pharmacokinetic and a broader spectrumof mechanism of efficacy, resp. more types of mechanis of efficacy may im-prove the therapeutic results in subtypes of bipolar disorder and in pharma-coresistent patients.
Key words: bipolar disorder, new anticonvulsants, lamotrigine, gabapentine,topiramat.
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