Medicinal products with controlled drug release for local therapy of inflammatory bowel diseases from perspective of pharmaceutical technology
Authors:
Kateřina Kubová
Authors‘ workplace:
Ústav farmaceutické technologie, Farmaceutická fakulta, Masarykova univerzita
Published in:
Čes. slov. Farm., 2020; 69, 112-120
Category:
Review Articles
Overview
The aim of this article is to introduce the basic design of used medicinal products with controlled drug release for the treatment of inflammatory bowel diseases and to clarify their behaviour in gastrointestinal tract from the perspective of pharmaceutical technology. Specifically, it focuses on pharmaceutical drugs containing 5-aminosalicylic acid (Asacol®, Pentasa®, Salofalk®) and budesonide (Budenofalk®, Cortiment®, Entocort®). As a part of this paper, basic recommendations and practical information that can be used in clinical practice are also given.
Keywords:
tablets – pellets – inflammatory bowel diseases – colon targeting – delayed drug release – pH-dependent polymers – capsules – granules – matrix – coating
Sources
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Pharmacy Clinical pharmacologyArticle was published in
Czech and Slovak Pharmacy
2020 Issue 3
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