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Minimally Invasive Glaucoma Surgery: iStent and Preserflo in the Treatment of Primary Open-Angle Glaucoma. A Review


Authors: Richard Ulrych 1;  Alexandr Stěpanov 1,2,3
Authors‘ workplace: Oblastní nemocnice Mladá Boleslav, a. s. 1;  3. lékařská fakulta Univerzity Karlovy v Praze 2;  Lékařská fakulta Slovenské zdravotnické univerzity v Bratislavě 3
Published in: Čes. a slov. Oftal., 82, 2026, No. 2, p. 67-71
Category: Review Article
doi: https://doi.org/10.31348/2025/39

Overview

Glaucoma is a chronic, progressive and irreversible neuropathy of the optic nerve, characterized by morphological changes in the optic nerve papilla and defects in the visual field. Although the precise pathogenesis is not fully understood, the current concept of glaucoma development incorporates the deformation of the lamina cribrosa caused by elevated intraocular pressure, leading to axonal damage, subsequent apoptosis of retinal ganglion cells and loss of the nerve fiber layer. This review article discusses the current possibilities of using minimally invasive glaucoma surgery, specifically focusing on the micro-invasive implants iStent and Preserflo, their efficacy and safety in the surgical treatment of primary open-angle glaucoma.

Keywords:

primary open-angle glaucoma – minimally invasive glaucoma surgery – Preserflo MicroShunt – iStent


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Ophthalmology
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