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Minimally Invasive Glaucoma Surgery: iStent and Preserflo in the Treatment of Primary Open-Angle Glaucoma. A Review


Authors: Richard Ulrych 1;  Alexandr Stěpanov 1,2,3
Authors‘ workplace: Department of Ophthalmology, Regional Hospital Mladá Boleslav, a. s., Czech Republic 1;  Third Faculty of Medicine, Charles University in Prague, Czech Republic 2;  Faculty of Medicine of the Slovak Medical University in Bratislava, Slovakia 3
Published in: Čes. a slov. Oftal., 81, 2025, No. Ahead of Print, p. 1-5
Category: Review
doi: https://doi.org/10.31348/2025/39

Overview

Glaucoma is a chronic, progressive and irreversible neuropathy of the optic nerve, characterized by morphological changes in the optic nerve papilla and defects in the visual field. Although the precise pathogenesis is not fully understood, the current concept of glaucoma development incorporates the deformation of the lamina cribrosa caused by elevated intraocular pressure, leading to axonal damage, subsequent apoptosis of retinal ganglion cells and loss of the nerve fiber layer. This review article discusses the current possibilities of using minimally invasive glaucoma surgery, specifically focusing on the micro-invasive implants iStent and Preserflo, their efficacy and safety in the surgical treatment of primary open-angle glaucoma.

Keywords:

minimally invasive glaucoma surgery – Preserflo MicroShunt – primary open-angle glaucoma – iStent


Labels
Ophthalmology

Article was published in

Czech and Slovak Ophthalmology

Issue Ahead of Print

2025 Issue Ahead of Print

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