The Incidence of Endophtalmitis after the Application of Intravitreal Injections in FNKV with Regard to Various Prophylactic Antibiotic Regimens
Authors:
Z. Straňák; M. Veith; P. Studený; M. Penčák
Authors‘ workplace:
Praha, přednosta kliniky
prof. MUDr. Pavel Kuchynka, CSc.
; Oftalmologická klinika, Fakultní
nemocnice Královské Vinohrady
Published in:
Čes. a slov. Oftal., 70, 2014, No. 5, p. 184-188
Category:
Original Article
Overview
Aim:
Comparing the incidence of endophtalmitis at the Ophthalmologic clinic of FNKV after the application of intravitreal injections with regard to various prophylactic antibiotic regimens.
Methodics:
Comparing the number of endophtalmitis cases during the period of 2005–2011, when the intravitreal applications were secured by full antibiotic prophylaxis (Floxal)/Oftaquix gtt. 5xd 3 days before the application and 3 days after the application with the years of 2012–2013, when Vigamox gtt. was used during the preparation of the eye before surgery to prevent inflammatory changes.
Results:
In the years of 2005–2013, 5005 injections were applied. In total we recorded three cases of endophthalmitis. In all cases, a pars plana vitrectomy with sample collection for culture and microbiological analysis was performed. During the years of 2005–2011, 2 651 injections were applied with two cases of endophtalmitis (0,075%, 1:1 325, both cases culture-negative). During the years of 2012–2013, 2 355 injections were applied with one case of endophtalmitis (0,042 %, 1:2 355, culture-positive).
Conclusion:
According to our experience, limited prophylactic antibiotic regimen does not increase the incidence of endophtalmitis in comparison with full prophylactic antibiotic regimen.
Key words:
intravitreal injections, antibiotic, endophtalmitis, prophylactic
Sources
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OphthalmologyArticle was published in
Czech and Slovak Ophthalmology
2014 Issue 5
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