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Xalatan (Latanoprost) as the First Choice Medication in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertension – Experience in the Czech Republic
Authors: P. Výborný; S. Sičáková
Authors‘ workplace: Oční klinika 1. LF UK a ÚVN, Praha, přednosta doc. MUDr. J. Pašta, CSc.
Published in: Čes. a slov. Oftal., 65, 2009, No. 6, p. 240-243
Category: Overview Report
Overview
The independent intervention study followed-up the efficacy of Latanoprost in 996 patients with primary open angle glaucoma and ocular hypertension during three months after the beginning of the treatment. The decrease of the intraocular pressure was clinically significant at the control as early as 1 month after the beginning of the treatment, and remained stable at the control after 3 months in the patients not treated ever before as well as in patients in whom the previous treatment by means of betablockers has not compensated the intraocular pressure. Latanoprost in the study showed good safety profile and was very well tolerated by the patients. Latanoprost is appropriate first choice medication in the primary open angle glaucoma and ocular hypertension treatment
Key words:
primary open angle glaucoma, ocular hypertension, latanoprost, intraocular pressure.
Sources
1. Alm A., Schoenfolder J., McDermott, J.: A 5-year, multicenter, open-label, safety study of adjunctive 0,005 % latanoprost once daily. Arch Ophthalmol 122, 2004, 957-965
2. Alm A., Stjernschantz J.: Effects of intraocular pressure and side effects of 0,005 % latanoprost applied once daily, evening or morning. A comparison with timolol. Scandinavian Latanoprost Study Group. Ophthalmology 103, 1996, 126-137
3. Dasgupta S., Oates V., Bookhart B., et al.: Population –based persistency rates for topícal glaucoma medication measured with pharmacy claims data. Am J Manag Care, 8, 2002, 255-261
4. Souhrn údajů o produktu. Registrace č..64/164/99-c. Poslední revize textu 21.8.2007
5. Terminology and guidelines for glaucoma, EGS,3rd Ed.,Dogma, 2008, 183 s. 6. The AIGS Investigators. The advanced glaucoma intervention study (AGIS). The relation between control of intraocular pressure and visual field determination. Am J Ophthalmol 130, 2000, 429-440
7. Výborný P., Fučík M., Rozsíval P.: Glaukom, 555 – 607. In: Kuchynka P. a kol.: Oční lékařství, Praha, Grada Publ., 2007, 768 s.
8. http://www.zelenyzakal.cz
Labels
Ophthalmology
Article was published inCzech and Slovak Ophthalmology
2009 Issue 6-
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