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Electroretinographic Findings in Age-related Macular Degeneration (ARMD) Before and after Radiotherapy


Authors: V. Korda;  J. Svěrák;  H. Langrová;  D. Hejcmanová;  P. Rozsíval;  J. Kvasnička;  K. Odrážka *
Authors‘ workplace: Oční klinika FN, Hradec Králové přednosta prof. MUDr. Pavel Rozsíval, CSc. ;  Klinika onkologie a radioterapie FN, Hradec Králové přednosta doc. MUDr. Jiří Petera, CSc. *
Published in: Čes. a slov. Oftal., 61, 2005, No. 5, p. 311-315

Overview

Standard ERG examinations were performed in 61 patients with ARMD before and after radiotherapy. Before the radiotherapy, a significant decrease in the cone b- wave amplitude and a significant reduction of the sum of oscillatory potentials (OP1–OP4) were found. At 24 months after the first dose of radiotherapy, a significant decrease in the rod response and 30-Hz flicker response were described. A possible explanation for the findings is an influence of radiotherapy onto primary circulatory disturbances in the whole retina in ARMD.

Key words:
electroretinography, age-related macular degeneration, radiotherapy


Labels
Ophthalmology
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