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Neuroprotektívny účinok pilokarpínua hladina kyseliny glutamovejv tkanivových štruktúrach zadnéhosegmentu oka
: J. Veselovský; Z. Oláh
: Katedra živočíšnej fyziológie a etológie Prír. Fak. UK, Bratislava, vedúci doc. RNDr. J. Veselovský, DrSc. Klinika oftalmológie LF UK, Bratislava, prednosta doc. MUDr. P. Strmeň, CSc.
: Čes. a slov. Oftal., , 1999, No. 2, p. 53-57
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V práci sú uvedené súvislosti s aplikovaním pilokarpínu v liečbe glaukómovéhoochorenia. Z pokusov in vivo na hovädzích očiach vyplýva, že pilokarpín popriovplyvnení tkanivových štruktúr predného segmentu oka s následným zníženímVOT preniká a pôsobí aj v tkanivových štruktúrach zadného segmentu oka. Pointerakcii s kyselinou glutamovou prispieva ku zachovaniu gangliových buniekcentrálnej časti sietnice a tým má brzdiaci vplyv na rozvoj morfologických i funkč-ných zmien pri glaukómovom ochorení.
Klíčová slova:
pilokarpín, kyselina glutamová v sietnici, glaukómové ochorenie
Labels
Ophthalmology
Article was published inCzech and Slovak Ophthalmology
1999 Issue 2-
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