S těhotenstvím související adenokarcinom plic s mutací EGFR v oblasti s endemickým výskytem tuberkulózy – diagnostická zkreslení a terapeutické překážky
Authors:
Dr. Muhammad Hafiz, SpP 1,2; Prof. Dr. Aziza G. Icksan 3; Dr. Ph. Sita Laksmi Andarini D, Ph.D, SpP 1,4,5; Dr. Nur M Karim, SpR 6; Dr. Annisa Dian Hari Hasari, SpP 2; Farhana Ibrahim Syuaib, MD 4,5; Dr. Retno Widyawati, SpPA 7; Dr. Tati Herdawati, SpPA 7
Authors‘ workplace:
Lung Cancer Center, MRCCC Siloam Hospitals Semanggi, Jakarta, Indonesia
1; Department of Pulmonology and Respiratory Medicine, Budhi Asih General Hospital, Jakarta, Indonesia
2; Department of Radiology, Universitas PRIMA, Medan, Indonesia
3; Division of Thoracic Oncology, Department of Pulmonology and Respiratory Medicine, Persahabatan Hospital, Jakarta, Indonesia
4; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
5; Department of Radiology, Budhi Asih General Hospital, Jakarta, Indonesia
6; Department of Anatomical Pathology, Budhi Asih General Hospital, Jakarta, Indonesia
7
Published in:
Klin Onkol 2026; 39(5): 372-377
Category:
doi:
https://doi.org/10.48095/ccko2026372
...
Sources
1. Jänne PA, Planchard D, Kobayashi K et al. Survival with osimertinib plus chemotherapy in EGFR-mutated advanced NSCLC. N Engl J Med 2026; 394 (1): 27–38. doi: 10.1056/nejmoa2510308.
2. Hendriks LE, Kerr KM, Menis J et al. Oncogene-addicted metastatic non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. Ann Oncol 2023; 34 (4): 339–357. doi: 10.1016/j.annonc.2022.12.009.
3. Cho BC, Lu S, Felip E et al. Amivantamab plus lazertinib in previously untreated EGFR-mutated advanced NSCLC. N Engl J Med 2024; 391 (16): 1486–1498. doi: 10.1056/nejmoa2403614.
4. Maemondo M, Inoue A, Kobayashi K et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 2010; 362 (25): 2380–2388. doi: 10.1056/NEJMoa0909530.
5. Rosell R, Carcereny E, Gervais R et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012; 13 (3): 239–246. doi: 10.1016/S1470-2045 (11) 70393-X.
6. Ocran Mattila P, Ahmad R, Hasan SS et al. Availability, affordability, access, and pricing of anti-cancer medicines in low - and middle-income countries: a systematic review of literature. Front Public Health 2021; 9 : 628744. doi: 10.3389/fpubh.2021.628744.
7. Bamodu OA, Chung CC. Cancer care disparities: overcoming barriers to cancer control in low - and middle--income countries. JCO Glob Oncol 2024; 10: e2300439. doi: 10.1200/GO.23.00439.
8. Amanda G, Susanto AD, Soehardiman D et al. Adenocarcinoma of the lung with positive epidermal growth factor receptor mutation in pregnancy. Lung India 2017; 34 (6): 548–551. doi: 10.4103/0970-2113.217574.
9. Zhou JP, Wang Y, Lin YN et al. Clinical features and management of lung cancer during pregnancy: a narrative review based on reported cases. Womens Health Rep (New Rochelle) 2023; 4 (1): 544–550. doi: 10.1089/whr.2023.0085.
10. Tversky A, Kahneman D. Judgment under uncertainty: heuristics and biases. Science 1974; 185 (4157): 1124–1131. doi: 10.1126/science.185.4157.1124.
11. Revannasiddaiah S, Madabhavi I, Thakur P et al. Undue delay in the diagnosis of lung cancer due to the clinician’s preoccupation with pre-existing tuberculosis. BMJ Case Rep 2011; 2011: bcr1020114932. doi: 10.1136/bcr.10.2011.4932.
12. Boussios S, Han SN, Fruscio R et al. Lung cancer in pregnancy: report of nine cases from an international collaborative study. Lung Cancer 2013; 82 (3): 499–505. doi: 10.1016/j.lungcan.2013.09.002.
13. Yang L, He YT, Kang J et al. Clinical features and intervention timing in patients with pregnancy-associated non-small-cell lung cancer. J Thorac Dis 2021; 13 (7): 4125–4136. doi: 10.21037/jtd-21-234.
14. Simons E, Camidge DR. Lung cancer oncogene-directed therapy, fertility, and pregnancy. J Thorac Oncol 2024; 19 (6): 866–876. doi: 10.1016/j.jtho.2024.01.003.
15. Mok TS, Kim SW, Wu YL et al. Gefitinib plus chemotherapy versus chemotherapy in epidermal growth factor receptor mutation–positive non–small-cell lung cancer resistant to first-line gefitinib (IMPRESS): overall survival and biomarker analyses. J Clin Oncol 2017; 35 (36): 4027–4034. doi: 10.1200/JCO.2017.73.9250.
Labels
Paediatric clinical oncology Surgery Clinical oncologyArticle was published in
Clinical Oncology
2026 Issue 5
-
All articles in this issue
- Kontinuita
- Can a negative PSMA PET/CT limit the indication for lymphadenectomy in patients with localized moderate- and high-risk prostate cancer?
- FLAURA2 – a step forward in first-line treatment of advanced EGFR-mutated non-small cell lung cancer
- Graft versus host disease as a marker for assessing quality of life in patients after allogeneic hematopoietic cell transplantation – results of a retrospective study
- Prediction of residual disease after chemotherapy in advanced NSGCT – does microRNA provide clinical benefits?
- With the exception of perinephritic fluid collection, all symptoms of TEMPI syndrome resolved following treatment for Waldenström macroglobulinemia
- Ivosidenib in the treatment of IDH1-mutated cholangiocarcinoma – a review of current evidence and case report demonstrating durable disease control
- Long term response to immunotherapy in a patient with low PD-L1 expression, high tumor mutational burden, and STK11 mutation
- Detection of RET fusion in late-line treatment of NSCLC followed by long-term disease control with selpercatinib
- Pregnancy-associated EGFR-mutant lung adenocarcinoma in a TB-endemic region – diagnostic bias and therapeutic barriers
- Diagnostic anchoring in metastatic adenocarcinoma – Was the turning point too late?
- Inhibice IDH u low-grade gliomů – horká současnost a zároveň racionální medicína
- Léčba nádorů GIT v éře precizní medicíny
- Aktuality z Národního ústavu pro výzkum rakoviny
- Clinical Oncology
- Journal archive
- Current issue
- Online only
- About the journal
Most read in this issue
- FLAURA2 – a step forward in first-line treatment of advanced EGFR-mutated non-small cell lung cancer
- Pregnancy-associated EGFR-mutant lung adenocarcinoma in a TB-endemic region – diagnostic bias and therapeutic barriers
- Kontinuita
- Can a negative PSMA PET/CT limit the indication for lymphadenectomy in patients with localized moderate- and high-risk prostate cancer?