Cultivating the calculation of clinical biochemistry analyte measurement uncertainties using biological variation and internal quality control

Overview

Measurement uncertainty is key parameter for assessment of analytical quality and also requirement for laboratory accreditation according to ISO 15189 : 2022. This publication shows wery poor state of situation in the level of calculation and presentation measurement uncertainty values in Czech republic. This work deals with current possibilites to elevate and harmonize these situation. Namely the recently created EFLM database of biological variation is recommended for using this purpose.

Keywords:

Measurement uncertainty – biological variation – ISO 15189 – EFLM – milano model