Authors: J. Vítovec 1; J. Špinar 2,3; L. Špinarová 1 Authors‘ workplace: I. interní kardioangiologická klinika LF MU a FN u sv. Anny v Brně 1; Interní kardiologická klinika LF MU Brno 2; Mezinárodní centrum klinického výzkumu, Brno 3 Published in: Kardiol Rev Int Med 2014, 16(5): 364-369 Category: Cardiology Review
Iron deficiency is an important co ‑ morbidity in patients with heart failure. A major factor in the pathogenesis of anaemia, it is also a separate condition with serious clinical consequences (e. g. impaired exercise capacity) and poor prognosis in heart failure patients. Experimental evidence suggests that iron therapy in iron ‑ deficient patients may activate molecular pathways that can be cardio ‑ protective. Clinical studies have demonstrated favourable effects of IV iron on the functional status, quality of life, and exercise capacity in HF patients. IV iron supplementation has become a novel therapy in HF patients with iron deficiency.
Keywords: anaemia – iron deficiency – heart failure – therapy of anaemia
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