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The benefit of measurement of B-type natriuretic peptide for monitoring the treatment of chronic cardiac failure


Authors: I. Málek;  M. Kubánek
Published in: Kardiol Rev Int Med 2007, 9(3): 154-158

Overview

Chronic heart failure is connected with the activation of sympatoadrenal and other humoral systems. Activation of vasoconstrictive/proliferative systems is to some extent counterbalanced by natriuretic peptides and other vasoactive substances. The evaluation of natriuretic peptides, especially BNP is valuable in the diagnosis of heart failure, assessment of actual hemodynamic status, development of symptoms and prognosis. However, there is not enough evidence that knowledge of BNP dynamics directly influence therapeutic decisions. In patients after heart transplantation increased blood concentration of BNP is not a consequence of acute rejection, but can be hold as a marker of subclinical graft damage, which could influence the fate of the patient.

Keywords:
B-natriuretic peptide – heart failure – cardiac transplantation


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Labels
Paediatric cardiology Internal medicine Cardiac surgery Cardiology
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