Diabetes treatment with hypolipidemic drugs and study ASPEN
Authors:
Š. Svačina
Published in:
Kardiol Rev Int Med 2006, 8(3): 112-113
Category:
Editorial
Overview
Type 2 diabetic patients are in extreme cardiovascular risk. The studies ASCOT-LLA a CARDS have showed a significant reduction of cardiovascular risk in diabetes using 10 mg atorvastatin. Recently finished the FIELD study did not show any significant risk reduction using fibrate. Statin was more frequently used in the placebo group and this could reduce the effect of fibrate in the comparison of both groups. 10 mg atorvastatin or placebo were used in the ASPEN study in type 2 diabetic patients in primary and secondary cardiovascular disease prevention. The design of the study and the changing guidelines cause two times higher use of other hypolipidemic drugs in the placebo group. ASPEN study does not bring controversies to older statin studies.
Keywords:
type 2 diabetes – statin – fibrate – cholesterol – macrovascular complications
Sources
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Paediatric cardiology Internal medicine Cardiac surgery CardiologyArticle was published in
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