New therapeutic modalities in the treatment of childhood acute lymphoblastic leukemia

Czech version

Authors: Šrámková Lucie
Authors‘ workplace: Klinika dětské hematologie a onkologie, 2. lékařská fakulta Univerzity Karlovy a Fakultní nemocnice v Motole, Praha
Published in: Čes-slov Pediat 2022; 77 (5): 265-271.
Category: Comprehensive Report
doi: https://doi.org/10.55095/CSPediatrie2022/042

Overview

Acute lymphoblastic leukemia (ALL) in children is a disease with a good chance of cure on current modern treatment protocols. Nevertheless, 10-15 % of children experience a relapse of the disease, some of them are already resistant to chemotherapy and require the use of additional treatment modalities. Of these new treatments, immunotherapy and other targeted drugs are already being used in current clinical practice, which have a very good effect even in significantly pre-treated patients and are gradually changing the concept of ALL treatment.

Keywords:

acute lymphoblastic leukemia – immunotherapy – relapse – targeted therapy

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