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Efficacy and Safety of High Doses of Enoxaparin in Preventing Thromboembolic Disease in Morbidly Obese Patients

28. 1. 2020 Source: Thromboprophylaxis

Thromboembolic disease is a significant cause of morbidity and mortality in hospitalized patients, with morbid obesity being a notable risk factor for thromboembolism. Various thromboprophylaxis strategies have been studied in morbidly obese patients; a recently published study compared the efficacy and safety of high doses of enoxaparin and unfractionated heparin.

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Prophylaxis of Thromboembolism with Low-Molecular-Weight Heparins in Oncology Patients: Efficacy and Safety of Doses Adjusted According to Anti-Xa Activity

Oncological patients undergoing surgical procedures are observed to have a high risk of thromboembolic complications. Recommended prophylactic dosing of low-molecular-weight heparins (LMWH) is often…
28. 1. 2020 Source: Thromboprophylaxis
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Evaluation of the m7-FLIPI score in patients with follicular lymphoma revealed a promising predictive biomarker for determining suitable chemotherapy

The authors of a study presented at the December congress of the American Society of Hematology (ASH) in Orlando introduced a new prognostic tool, m7-FLIPI, for determining the risk level of patients…
27. 1. 2020 Source: Non-Hodgkin Lymphomas and CLL
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Kadcyla in a New Indication –⁠ Adjuvant Therapy for Early HER2+ Breast Cancer

In December, the European Commission approved the expansion of the indication for Roche's medicinal product Kadcyla, which contains the active substance trastuzumab emtansine. This expansion makes…
23. 1. 2020 Source: Breast Carcinoma

Comparison of Safety and Efficacy of Oral and Intravenous Administration of Combination NEPA in the Prophylaxis of Chemotherapy-Induced Nausea and Vomiting

Both oral and intravenous administration of a combination of netupitant (a neurokinin 1 receptor antagonist −⁠ NK1RA) with palonosetron (a 5-HT3 receptor antagonist) offer prevention of…
20. 1. 2020 Source: Antiemetic Therapy

Cost Effectiveness of Netupitant/Palonosetron Combination in the Prophylaxis of Chemotherapy-Induced Nausea and Vomiting

A recently published study compared the costs of achieving a complete response to antiemetic therapy in the prophylaxis of chemotherapy-induced nausea and vomiting (CINV) when using a combination of…
20. 1. 2020 Source: Antiemetic Therapy
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Impact of Oral Antidiabetics on Heart Failure

Diabetes mellitus is primarily perceived as a risk factor for ischemic heart disease and general atherosclerotic complications. However, an equally significant problem is the association between diabetes...
19. 1. 2020 Source: Diabetes
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Position of Levodropropizine in Cough Therapy

An international group of specialists focused in 2016–2017 on a detailed evaluation of current options for cough therapy. The authors based their analysis on individually prepared reviews using…
15. 1. 2020 Source: Cough Therapy

Cost Effectiveness of FVIII Substitution Versus Non-Factor Therapy for Hemophilia A

With new treatment options for hemophilia A without inhibitors, the question of cost-effectiveness of different treatment approaches arises. The results of a model comparing replacement therapy and…
15. 1. 2020 Source: Hemophilia
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The World of Viruses is Constantly Evolving and Bringing Us New Surprises

The last decade has been marked by the emergence of new, as well as re-emerging human pathogens responsible for various infectious diseases. Viruses, especially those of zoonotic origin that originate...
13. 1. 2020 Source: Anti-Infectives
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