News
After 20 years, a new treatment option for primary biliary cholangitis arrives
Primary biliary cholangitis (PBC), formerly known as cirrhosis, is a rare disease with a negative impact on prognosis and quality of life. While ursodeoxycholic acid (UDCA) has been essentially the only treatment option for PBC so far, in 2016, the European Medicines Agency (EMA) approved obeticholic acid as a second-line option. Since 2019, this medication has been available and fully covered by health insurance in 11 selected centers in the Czech Republic.
Osimertinib in the Treatment of Patients with NSCLC with Secondary EGFR T790M Mutation – Case Study
Non-small cell lung cancer (NSCLC) is a genetically heterogeneous disease. Individualization of…
Chronic Thromboembolic Pulmonary Hypertension – Overview of Pathophysiology, Diagnosis, and Treatment
Chronic thromboembolic pulmonary hypertension (CTEPH) is defined by the 2015 ESC/ERS guidelines as…
Effect of Cataract Surgery on Melatonin Secretion in Adults Aged 60 and Over
A study by ophthalmologists and epidemiologists from Nara University in Japan, recently published…
Morning Myopic Shift and Glare in Patients with Advanced Fuchs Endothelial Corneal Dystrophy
A newly published study by a German team analyzes the morning and afternoon differences in various…
Venetoclax in the Treatment of CLL: Open Doors for the Longest Possible Maintenance of Remission Without Active Therapy
William G. Wierda from MD Anderson Cancer Center in Houston, USA, and Francesco P. Tambaro from…
Temporary Interruption of Treatment or Dose Modification of Ibrutinib in CLL Patients
A team from the Mayo Clinic in Rochester, USA, published a study this March in the journal Cancer…
Valproate and Lithium in Maintenance Therapy of Bipolar Affective Disorder
Among the so-called mood stabilizers, drugs commonly used in the therapy of bipolar affective…
Anticonvulsants Are Associated with the Least Impact on Sexual Function in Bipolar Disorder Treatment
It is known that in patients with bipolar disorder, in addition to the illness itself, sexual…
Study PLATON: romiplostim in patients with ITP in real clinical practice
Recently, the results of the PLATON study with romiplostim, which was conducted in Central and…
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