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Current Indication Criteria for Testing Mutations in BRCA1 and BRCA2 Genes in Breast and Ovarian Cancer
Testing the mutation status of the BRCA1/2 genes can be beneficial for prevention, and in the case of already detected breast and/or ovarian cancer, also for direct treatment. We provide a brief overview of the current recommendations for testing based on the 2019 NCCN (National Comprehensive Cancer Network) guidelines and the recommended procedures of the Society of Medical Genetics ČLS JEP.
Aclidinium bromide improves the quality of life for COPD patients
The ON-AIR study conducted in real practice demonstrated the benefits of aclidinium bromide for the…
Study AMPLIFY Confirmed Safety and Efficacy of Fixed Combination Aclidinium/Formoterol in COPD Therapy
The randomized double-blind phase III AMPLIFY study compared the efficacy of a fixed combination of…
Efficacy of L. reuteri DSM 17938 in Treating Acute Gastroenteritis in Children
Diarrheal diseases are among the most common causes of death worldwide in children under 5 years of…
The Importance of Early Diagnosis and Treatment of AATD in Preventing Pulmonary Emphysema
Alpha-1 antitrypsin deficiency (AATD) is a risk factor for the development of various diseases,…
Deficit Alpha-1-Antitrypsin as an Underestimated Problem? What a Survey Among European Experts Revealed
Alpha-1-antitrypsin deficiency (AATD) is a congenital disorder caused by mutations in the SERPINA1…
Does Tofacitinib Improve Comorbid Depressive and/or Anxiety Symptoms in Patients with Rheumatoid Arthritis?
Depression and anxiety disorders are commonly observed in patients with rheumatoid arthritis and…
Efficacy of Reduced Dose Tumor Necrosis Factor Inhibitors in Axial Spondyloarthritis
The introduction of tumor necrosis factor inhibitors marked a breakthrough in the treatment of…
Effect of Combination of Dorzolamide with Timolol for Wet Age-Related Macular Degeneration
In some eyes with wet age-related macular degeneration (AMD), exudation does not stop despite…
Minimum and Optimal Factor Levels in Physically Active Hemophiliacs
Authors of a recently published study attempted to determine the value of minimum and optimal…
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