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Efficacy and Tolerance of Dorzolamide/Timolol Combination With and Without Preservatives in Patients With Elevated Intraocular Pressure
The fixed combination of the carbonic anhydrase inhibitor dorzolamide and the locally acting beta-blocker timolol is indicated for the treatment of elevated intraocular pressure in patients with open-angle glaucoma. The comparison of the efficacy and tolerance of this combination with preservatives, associated among other things with eye irritation, and without them was the subject of the American study presented below.

Self-administration of alpha-1-antitrypsin can significantly improve patients' quality of life
Treatment of alpha-1 antitrypsin deficiency (AATD) requires lifetime administration of weekly…

Treatment of Glaucoma: Without Preservatives for Everyone?
A comprehensive report by Professor John Thygesen from the University Hospital in Copenhagen…

Pharmacokinetics and Safety of Bilastine 10 mg in Children Aged 6–11 Years
The second-generation antihistamine bilastine is approved in Europe for the treatment of allergic…

Safety and Tolerability of Bilastine in the Treatment of Chronic Urticaria in Children
Chronic urticaria is less common in pediatric patients compared to the acute form, but it always…

Transition of Hemophilia A Patients with a History of Coagulation Factor Inhibitor to Emicizumab
During the World Federation of Hemophilia (WFH) conference, held virtually in June 2020,…

DPP-4 Inhibitors May Prevent SARS-CoV-2 Entry into Cells
Since the new type of coronavirus SARS-CoV-2 utilizes the DPP-4 receptor to enter human cells,…

An Introductory Word to the Section on Hereditary Angioedema — MUDr. Roman Hakl, Ph.D.
Hereditary angioedema (HAE) is a genetically conditioned disease, currently classified into HAE…

Algorithm for Choosing Antidiabetics in Patients with Type 2 Diabetes
As of June 1, 2020, general practitioners can prescribe antidiabetics from the group of so-called…

Major Orthopedic Procedures in Patients with Inhibitor Treated with Emicizumab
Italian authors presented the results of a study of a small series of hemophilia patients with…
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