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Neoadjuvant Immunotherapy in Resectable Non-Small Cell Lung Cancer
Antibodies against the programmed cell death protein 1 (PD-1) improve the survival of patients with advanced non-small cell lung cancer (NSCLC). However, their use has not yet been tested in patients with resectable NSCLC. In 2018, the New England Journal of Medicine published the results of a pilot study of neoadjuvant therapy with nivolumab in patients with resectable NSCLC. Based on the promising results of this study, the investigative team subsequently decided to also test a combination of nivolumab and ipilimumab.
Impact of Alpha-1 Antitrypsin Deficiency on Quality of Life and Mental Health of Patients
The clinical manifestation of alpha-1 antitrypsin deficiency and its impact on quality of life are…
COVID-19 and Immune Thrombocytopenic Purpura − Spanish Experience Suggests Surprising Connections
In a retrospective study examining the impact of COVID-19 on immune thrombocytopenic purpura,…
Care of Dental Dentures According to the Recommendations of the American Society of Dental Prosthetists
Dental dentures are the most common solution for missing teeth in the jaw. They should serve…
Current Insights into the Antispasmodic and Analgesic Effects of Metamizole on the Gastrointestinal Tract
Brazilian authors published a review of available information on the mechanism of action of…
Impact of Thyroid Dysfunction on the Cardiovascular System in Elderly Patients
The incidence of thyroid disease increases with age. In the Czech Republic, up to 5% of the…
Rurioctocog alfa pegol in previously treated patients with severe hemophilia A: What findings did the long-term continuation study bring?
Rurioctocog alfa pegol (Adynovi) is a recombinant coagulation factor VIII modified by pegylation,…
Position of aPCC in the Treatment of Hemophilia A Complicated by the Development of Inhibitors
Activated prothrombin complex concentrates (aPCC) are essential drugs that not only allow the…
Anxiety Disorders and Autoimmune Thyroiditis – A Connection Rather Than Coincidence?
Anxiolytics commonly target the central nervous system. Newly published research by Ukrainian…
Targeted Treatment and Quality of Life in Patients with Follicular Lymphoma
The GALLIUM clinical trial evaluated chemotherapy in combination with targeted treatment using…
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