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View on the Treatment of Rheumatoid Arthritis with Baricitinib Using the NNT Indicator

30. 11. 2020 Source: Biological Treatment

Clinical parameters assessed by patients themselves are an important tool in evaluating the effectiveness of new drugs and are particularly significant in the evaluation of treatments for chronic painful conditions, such as rheumatoid arthritis (RA). An analysis of clinical trial results presented at the European Rheumatology e-Congress in June 2020 focused on the effectiveness of the Janus kinase inhibitor baricitinib on parameters assessed directly by patients. Effectiveness was analyzed using the NNT indicator.

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Shared Decision-Making on Kidney Function Replacement

Peritoneal dialysis (PD) is not a new development, but its significance is becoming increasingly…
30. 11. 2020 Source: Chronic Kidney Disease

Options for Modifying and Improving the Efficiency of the HJHS Scoring System

The Hemophilia Joint Health Score (HJHS) is a validated tool for assessing joint health in…
30. 11. 2020 Source: Hemophilia with Movement
fyzioterapie ergoterapie cvičení

Physiotherapy as Part of Comprehensive Care for People with Hemophilia –⁠ Recommendations vs. Reality

It appears that the physiotherapeutic care provided in reality to people with hemophilia does not…
30. 11. 2020 Source: Hemophilia with Movement
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Use of Brodalumab in the Treatment of Severe Plaque Psoriasis −⁠ Case Report

The case report by MUDr. Jan Šternberský, Ph.D., from the Clinic of Skin and Venereal Diseases, UP…
28. 11. 2020 Source: Topical Treatment of Psoriasis
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Hypotension during treatment with sacubitril/valsartan: practical tips for prevention and management

Despite the undeniable benefits of sacubitril/valsartan in terms of morbidity and mortality in…
27. 11. 2020 Source: Chronic Heart Failure and Lipidology

Is it possible to predict survival time based on laboratory or radiological findings in patients with IPF?

High-resolution computed tomography (HRCT) imaging of the lungs is a fundamental examination in…
26. 11. 2020 Source: Pulmonary Fibrosis
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Gliflozins in the Treatment of Type 2 Diabetes According to Current Recommendations SVL

Gliflozins are a relatively new group of antidiabetics with a specific mechanism of action. In…
24. 11. 2020 Source: Diabetes
mereni_tepu

Combination of Arterial Hypertension and Increased Heart Rate as a Significant Cardiovascular Risk Factor

Heart rate is one of the basic vital signs that should be regularly measured. Sinus tachycardia can…
23. 11. 2020 Source: Cardiovascular Continuum
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Is Six Months of Adjuvant Targeted Therapy Sufficient for Early Breast Cancer?

The inclusion of adjuvant targeted therapy with chemotherapy for early HER2-positive breast cancer…
23. 11. 2020 Source: Breast Carcinoma
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