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Is Six Months of Adjuvant Targeted Therapy Sufficient for Early Breast Cancer?
The inclusion of adjuvant targeted therapy with chemotherapy for early HER2-positive breast cancer significantly improved patient outcomes. Since 2006, based on data from registration studies, the gold standard for adjuvant therapy has been 12 months of trastuzumab administration. However, similar effects were observed in a smaller study with just 9 weeks of treatment. The presented clinical trial therefore investigated the non-inferiority of shorter treatment duration (6 months).
Targeted Treatment of Metastatic Breast Cancer in the 2nd Line – Experiences from Practice
The recommended treatment for metastatic HER2-positive breast cancer in the 1st line involves dual…
Micronutrients in Parenteral Nutrition in Adult Patients – Current Issues and Consensus
Micronutrients are a key nutritional component, and this is also true for patients whose condition…
Residual Pulmonary Hypertension After Endarterectomy: How Common Is It?
Pulmonary endarterectomy is the only potentially curative option in the treatment of chronic…
Medium to Long-term Results of PFC Sigma Total Knee Arthroplasty
The PFC Sigma knee implant was introduced in 1997. It is the most commonly used system for total…
Venous Insufficiency of the Lower Extremities – A Diverse Range of Risks, Manifestations, and Complications
Although initially often asymptomatic, chronic venous insufficiency includes a variety of symptoms.…
Geriatrics and Nutrition in Old Age - Invitation
We invite you to watch a webinar dedicated to the topic of nutrition in old age. The impetus for its...
Effect of Zolpidem on the Quality of Overnight Sleep in Terms of Episodic Memory Formation
Zolpidem is a non-benzodiazepine hypnotic used for the short-term treatment of insomnia in adults.…
Idiopathic Pulmonary Fibrosis: What Can a General Practitioner Do?
When a previously healthy patient becomes breathless, it's never good news. Among the particularly…
Direct Oral Anticoagulants and Their Reversal Agents – Current Options
In the last 10 years, the options for anticoagulant therapy have expanded with the introduction of…
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