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How Do Sleep and Depression Influence Each Other?

27. 10. 2021 Source: Depression and Anxiety

It is known that most patients with depression encounter some form of sleep disorder. In the following text, we briefly explore the complex relationship between depression and sleep and offer some practical recommendations that can help patients improve their sleep.

Dítě_kašel_postel

Conditions for the Use of Mucolytics in Children Are Tightening in Europe −⁠ Which Treatment Is Preferred?

There has been a long-standing discussion among experts regarding the benefits of individual mucomodulatory drugs in the treatment of productive cough in children. According to current…
25. 10. 2021 Source: Cough Therapy
krvácení, nos, krev, bolest

Optimization of Romiplostim Administration in ITP Treatment

In their newly published review article, authors from several American institutions summarize findings on the role of romiplostim in the treatment of immune thrombocytopenia (ITP) and its efficacy…
22. 10. 2021 Source: Immune Thrombocytopenia
žena, únava, bolest

Fatigue as a Significant Symptom of Immune Thrombocytopenia from the Patients' Perspective

The I-WISh survey assessed the impact of immune thrombocytopenia (ITP) and its treatment on patients' lives. Patients identified fatigue as the most frequent, severe, and persistent symptom…
22. 10. 2021 Source: Immune Thrombocytopenia
hemofilie skumavka

Final Analysis of the STASEY Study: How Did Emicizumab Fare in the Prophylaxis of Hemophilia A Patients with FVIII Inhibitors?

The July virtual congress of the International Society on Thrombosis and Haemostasis (ISTH) 2021 offered a variety of interesting topics. Among the poster presentations, data from the multicenter, single-arm,...
21. 10. 2021 Source: Rare Diseases in Hematology
roztroušená skleróza_ mašle_ruce

Alemtuzumab –⁠ Does Age Matter? Or Not?

The authors of a study published this year focused on the safety and efficacy of alemtuzumab in patients with relapsing-remitting multiple sclerosis (RRMS). How did it perform over the observed…
18. 10. 2021 Source: Multiple Sclerosis
roztroušená skleróza_mozek_ puzzle

Does Teriflunomide Bloom at Every Age?

What impact does age have on the effectiveness of multiple sclerosis (MS) therapy in real-world clinical practice? How do the outcomes differ for patients treated with teriflunomide considering their…
18. 10. 2021 Source: Multiple Sclerosis
Senior_Alzheimer

How Does Memantine Currently Stand in Alzheimer's Disease and Other Dementias

A comprehensive meta-analysis from 2019 examined the effect and safety of administering memantine, particularly in patients with moderate to severe Alzheimer's disease. How did memantine fare?
17. 10. 2021 Source: Cognitive in the treatment of Alzheimer's disease
covid lékař pacientka nemocnice koronavirus vyšetření

Treatment of Metastatic Colorectal Cancer During the COVID-19 Pandemic

In the conditions of the coronavirus pandemic, it is difficult to maintain good accessibility to ongoing comprehensive oncological care, and thus the quality of life of patients. An international…
15. 10. 2021 Source: Treatment of Gastrointestinal Carcinomas
plíce

Biosimilar MB02 as an Alternative to Bevacizumab in Lung Cancer Treatment

The STELLA clinical trial aimed to evaluate the efficacy, safety, and immunogenicity of MB02, a biosimilar to bevacizumab, in patients with advanced non-small cell lung cancer.
15. 10. 2021 Source: Oncological Treatment
Onkologická pacientka chemoterapie

Efficacy and Safety of Gefitinib in Combination with Chemotherapy vs. Chemotherapy Alone in the Treatment of Advanced NSCLC

Non-small cell lung cancer (NSCLC) remains a disease with high mortality. The meta-analysis presented below compared the efficacy and safety of gefitinib in combination with chemotherapy versus…
15. 10. 2021 Source: Oncological Treatment
Výtěr z nosu_muž

Nasal Smear as a Modern and Gentle Diagnostic Method for Allergic Rhinitis

Up to 130 million Europeans suffer from allergic rhinitis. Until now, standard diagnostic methods have been skin prick tests and laboratory blood tests. Both methods, however, present significant…
14. 10. 2021 Source: Allergic Reactions
immune thrombocytopenia

Physiological and Clinical Effect of Romiplostim in the Treatment of ITP

Romiplostim in the treatment of immune thrombocytopenia (ITP) has demonstrated safety and the promise of long-term remission, enabling many pediatric and adult patients to discontinue treatment and…
11. 10. 2021 Source: Immune Thrombocytopenia
immune thrombocytopenia2

Administration of Romiplostim in Patients with ITP in Real-World Practice in Central Europe

Data from the PLATON study on the administration of romiplostim in real-world clinical practice in Central and Eastern Europe confirmed very good efficacy in patients with newly diagnosed,…
11. 10. 2021 Source: Immune Thrombocytopenia
ockovani covid-19 muž

Vaccination Against COVID-19 in Patients Treated With Anticoagulants

Canadian professional societies and the National Health Service (NHS) in the United Kingdom recommend COVID-19 vaccination even for patients treated with anticoagulants. The benefit of vaccination in…
11. 10. 2021 Source: Anticoagulant Treatment
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