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How to Properly Treat Frostbite?

7. 12. 2021 Source: Wound Healing

Frostbite, or congelation, is defined as an acute condition involving damage to the skin and subcutaneous tissues due to local cold, particularly at subzero temperatures. Treatment requires quality care. By choosing the right therapy, we can prevent complications that might otherwise threaten the patient with amputation of the affected part. The healing process is lengthy and requires patience from both the patient and the attending physician.

Prognostic Model MSKCC in Patients with Metastatic Renal Carcinoma Treated in 1st Line with Sunitinib

A study by Czech authors published in 2020 demonstrated the usefulness of the MSKCC (Memorial Sloan Kettering Cancer Center) model in the prognostic stratification of patients with metastatic renal…
6. 12. 2021 Source: Kidney Carcinoma
plice lekar 2

Treatment of COPD in Individuals with Alpha-1 Antitrypsin Deficiency

A mutation in the gene for alpha-1 antitrypsin (AAT), leading to its deficiency (AATD), causes progressive irreversible destruction of lung tissue. Patients develop chronic obstructive pulmonary…
6. 12. 2021 Source: Deficiency of Alpha-1-Antitrypsin
lekari v ordinaci pocitac overeni informace

Can the Treatment of Hypertension Prevent Recurrence of Atrial Fibrillation?

Atrial fibrillation (Afib) is the most common serious heart rhythm disorder and is responsible for a significant portion of deaths in the population. Hypertension is the most common and potentially…
3. 12. 2021 Source: Sartans in the Treatment of Hypertension
doktor_stetokop

Reduction of Risk of Hospitalizations for Heart Failure in Type 2 Diabetics

The EMPA-REG OUTCOME study already in 2015 highlighted one of the benefits of the sodium-glucose cotransporter 2 (SGLT2) inhibitor empagliflozin, which is the reduction of the risk of hospitalization…
2. 12. 2021 Source: Heart Failure
imunoglobulin

Recommendations for Substitution Therapy with Immunoglobulins in Hemato-oncological Patients with Secondary Immunodeficiency –⁠ Expert Consensus According to the DELPHI Methodology

Substitution therapy with immunoglobulins is used not only for patients with primary immunodeficiencies. Below, we briefly summarize recommendations concerning hemato-oncological patients with secondary...
1. 12. 2021 Source: Primary and Secondary Immunodeficiencies
vaha doktor pacient

How Does Emicizumab Work in Obese Adults with Hemophilia A?

What is the annual bleeding rate and minimum concentration of emicizumab in obese adults with hemophilia A compared to non-obese individuals? Answers were sought by the authors of a pooled post hoc…
1. 12. 2021 Source: Quality Life Even with Hemophilia
klinicka studie

Romiplostim in Routine Clinical Use among Patients with ITP in European Countries −⁠ Fresh Data Analysis

Data from randomized clinical trials have shown that romiplostim is an effective medication for many patients not only with acute or persistent immune thrombocytopenia (ITP) but also for much more…
30. 11. 2021 Source: Immune Thrombocytopenia
Analýza dat

How TPO-RA Drugs Fared in Meta-Analyses of Safety and Efficacy in ITP Patients

Meta-analyses regarding the use of thrombopoietin receptor agonists (TPO-RA) evaluated their efficacy and safety in the treatment of primary immune thrombocytopenia over long-term follow-ups. What…
30. 11. 2021 Source: Immune Thrombocytopenia
Ledviny_ruce

Expanded Hemodialysis and Its Impact on Reducing Hospitalization Rates and Medication Usage

The number of patients with end-stage kidney disease is increasing. New approaches and technological advancements in recent decades have contributed to improving hemodialysis treatment. Does the use…
30. 11. 2021 Source: Chronic Kidney Disease
Karcinom plic

Efficacy of Brigatinib in Patients with Metastatic NSCLC −⁠ Real-World Clinical Data

The journal Lung Cancer published the results of a retrospective analysis of the efficacy of brigatinib in patients with ALK-positive metastatic non-small cell lung cancer (NSCLC) who participated in…
29. 11. 2021 Source: Non-Small Cell Lung Cancer
sepse, krvinky

Monocyte Distribution Width Indicates Sepsis Regardless of Sepsis Etiology

Patients in intensive care units represent a high-risk population for the development of sepsis, which is one of the primary causes of mortality in these settings. The aim of the recently published…
29. 11. 2021 Source: Because
sepse, nebezpečí

News in Laboratory Diagnostics of Early Sepsis −⁠ First Czech Experiences

Sepsis represents one of the most frequent causes of morbidity and mortality in critically ill patients. Laboratory markers play an important role in the diagnosis and prognosis of septic states. The…
29. 11. 2021 Source: Because
analýza krve skumavky

Final Analysis of the STASEY Study: How Did Emicizumab Perform in Prophylaxis of Hemophilia A Patients with FVIII Inhibitors?

The July virtual congress of the International Society on Thrombosis and Haemostasis (ISTH) 2021 offered a range of interesting topics. In its poster section, data from the multicenter single-arm…
29. 11. 2021 Source: Quality Life Even with Hemophilia
fotbal dite zraneni

What does the analysis of the CHESS PAEDs study say about the relationship between physical activity and the frequency of bleeding events in children with hemophilia A?

Currently, there is limited published data addressing the relationship between physical activity and the occurrence of bleeding events in children with hemophilia A. To gain insights into this topic…
27. 11. 2021 Source: Quality Life Even with Hemophilia
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