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lékař_pacient

Long-term Efficacy, Safety, and Tolerability of Normal Human IgG with Facilitated Absorption in Patients with Humoral Immunodeficiency

12. 1. 2023 Source: Primary and Secondary Immunodeficiencies

The treatment of patients with humoral immunodeficiency is long-term and therefore needs to be not only effective but also safe and well-tolerated. Below, we present the outcomes from an Italian real-world clinical practice study evaluating the efficacy, safety, and tolerability of human immunoglobulin for facilitated subcutaneous administration and patient satisfaction with this therapy.

Lékař_pacient

fSCIG in Elderly Patients with PID or SID in Real Clinical Practice

The work of a team of German and Dutch authors presents data on the real clinical use of 10% subcutaneous immunoglobulin facilitated by hyaluronidase (fSCIG) in elderly patients with primary (PID) or…
12. 1. 2023 Source: Primary and Secondary Immunodeficiencies
Guidelines_kompas

Current NCCN Recommendations for Classification and Risk Symptoms in SLL/CLL

The new recommendations from the National Comprehensive Cancer Network (NCCN) regarding chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) from August 2022 also include a brief…
12. 1. 2023 Source: Chronic Lymphocytic Leukemia
Vaporizer_muž

Electronic Cigarettes as an Alternative Option for Quitting Smoking?

Diseases caused by smoking tobacco products are a significant cause of global morbidity and mortality. One of the options for quitting smoking is electronic cigarettes, which, although not entirely…
12. 1. 2023 Source: MDT Board
srdce a diabetes

Diabetes mellitus and heart failure −⁠ interconnected units with complex pathogenesis

Diabetes mellitus (DM) represents a significant risk factor for the development of heart failure. The pathogenesis of this condition is very complex, involving hyperglycemia and other metabolic…
12. 1. 2023 Source: Heart Failure
žena_vozík

Teriflunomide "under the microscope" or what it's like to live with MS in the North

The Teri-LIFE study examined teriflunomide very comprehensively. How does it manage to affect the quality of life of patients with multiple sclerosis (MS) according to data from real clinical…
12. 1. 2023 Source: Multiple Sclerosis
kardiologie výzkum

Cardiovascular Interventions with Continued Therapy with Dabigatran −⁠ Insights from the GLORIA-AF Study

An analysis using data from an international registry of patients with newly diagnosed atrial fibrillation evaluated the safety and efficacy of continued therapy with dabigatran during cardioversion…
12. 1. 2023 Source: Anticoagulant Treatment
magnetická_rezonance

Smouldering Multiple Sclerosis: How Can MRI Help in Its Identification?

With the changing understanding of the etiopathogenesis of multiple sclerosis, several new questions arise. One of them is the question of identifying the progressive phase of the disease. Can…
4. 1. 2023 Source: Multiple Sclerosis
léky_tablety

Teriflunomide vs. Dimethyl Fumarate: Does Their Classification into Different Treatment Lines Have Merit?

Teriflunomide is one of the first-choice medications in the treatment of multiple sclerosis (MS) patients, not only in the Czech Republic. Conversely, the use of dimethyl fumarate is more limited…
4. 1. 2023 Source: Multiple Sclerosis
nemocnice příjem čekárna

Prevalence of Heart Failure and Its Subtypes in the Population of Developed Countries

In developed countries, heart failure occurs in approximately 2% of the population, with an annual incidence of 5-10/1000 inhabitants. The mortality rate for patients with chronic heart failure is…
2. 1. 2023 Source: Heart Failure
dyslipidémie

Inclisiran −⁠ a new addition to the arsenal of dyslipidemia treatment

At the XXIX Congress of the Czech Society of Internal Medicine ČLS JEP, held November 6−9, 2022 in Prague, lectures on innovative dyslipidemia therapy using the small interfering RNA molecule −…
23. 12. 2022 Source: Chronic Heart Failure and Lipidology
LDL cholesterol

Use of Inclisiran in a Patient in Secondary Cardiovascular Prevention

Lowering LDL cholesterol (LDL-c) is one of the primary goals for reducing cardiovascular (CV) risk due to its proven mortality reduction. However, many patients with familial hypercholesterolemia or…
23. 12. 2022 Source: Chronic Heart Failure and Lipidology
fokální záchvaty

Cenobamate −⁠ A Case Study from Slovak Real Practice

Cenobamate is indicated for adjunctive therapy of focal seizures with or without secondary generalization in adult patients who have not achieved sufficient results with previous treatment with at…
23. 12. 2022 Source: Epilepsy
karcinom plic_lékař

Brigatinib in the Therapy of Pretreated Patients with Advanced ALK-Positive NSCLC

A French study analyzed clinical data of pretreated ALK-positive patients with advanced non-small cell lung cancer (NSCLC) and examined the efficacy of next-generation ALK inhibitors –⁠ brigatinib,…
22. 12. 2022 Source: Non-Small Cell Lung Cancer
mnohočetný myelom

Addition of ixazomib to lenalidomide and dexamethasone in multiple myeloma −⁠ Data from real-world Czech practice

A group of Czech and Slovak experts led by Associate Professor Jiří Minařík from the Hemato-Oncology Clinic of the Faculty of Medicine UP and University Hospital Olomouc published the final results…
22. 12. 2022 Source: Hematologic Malignancies
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