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Diagnosis of Cow Milk Protein Allergy −⁠ Current Methods and Their Diagnostic Value

15. 2. 2023 Source: GI, colic and microbiome

Cow milk protein allergy (CMPA) is among the most common pediatric food allergies. In case of early reaction, the child should be immediately referred to an allergist; for delayed symptoms, an elimination-exposure test can be performed under the guidance of a pediatrician.

Suché oko

Etiology and Therapy of Dry Eye Syndrome in a Nutshell

Dry eye syndrome, the most common diagnosis in outpatient ophthalmology practice, is a multifactorial disease with varying severity of symptoms. It reduces the quality of life and can also affect the…
15. 2. 2023 Source: Ophthalmologic Diseases
alzheimer hlava deda

At the Crossroads: 5 Options for Alzheimer's Disease Pharmacotherapy

Currently, we have 5 basic options for the pharmacotherapy of Alzheimer's disease. Is memantine, one of the three cholinesterase inhibitors, or combination therapy the most effective? A review…
9. 2. 2023 Source: Viral infections
Colours of Sepsis 20231

Colours of Sepsis 2023: Antimicrobial Stewardship is a Necessity. The Spectrum of Effective Antimicrobial Modalities has Expanded to Include Another Combination

Inappropriate antibiotic (ATB) treatment is associated with high mortality, while unrestricted use of broad-spectrum antibiotics drives resistance development. Thus, the decision to deploy…
9. 2. 2023 Source: Anti-Infectives
Protonové centrum

Proton radiotherapy means lower risk with high efficacy of radiation. The key is getting the patient into the treatment process as soon as possible

The Proton Therapy Center in Prague (PTC −⁠ Proton Therapy Center Czech) is a modern healthcare facility specializing in the treatment of oncological diseases using so-called proton radiotherapy. This…
8. 2. 2023 Source: Proton Radiotherapy
telemonitoring

The Unexpected Rise of Telemonitoring During the COVID-19 Pandemic

The COVID-19 pandemic, despite many negative impacts, also brought positive benefits to patients' health in a rather unexpected direction. Prior to the coronavirus pandemic, monitoring basic vital…
8. 2. 2023 Source: proLékaře.cz
proteiny v mozku

Transthyretin –⁠ More Than a Thyroxine Transporter

Transthyretin (TTR) is an extracellular protein whose main role is to transport thyroxine and retinol in the body and brain. TTR tends to form amyloid deposits, which can lead to systemic disease…
6. 2. 2023 Source: Amyloidosis
muž ve středních letech u lékaře

Patient with a History of DOAC Usage in Neurological ICU with Stroke –⁠ Case Study

How should we approach patients with a stroke who are taking direct oral anticoagulants (DOACs) and correctly assess the situation? When should we administer the available antidote according to…
1. 2. 2023 Source: Anticoagulant Treatment
f VIII hemofilie

Critical Overview of Clinical Studies on EHL FVIII Preparations

An international team of experts recently published a comprehensive work evaluating the methodology used in clinical trials of various extended half-life (EHL) factor VIII (FVIII) products. Their…
1. 2. 2023 Source: Hemophilia
astma kluk

Overview of Regimen Measures for House Dust Mite Allergy

House dust mite allergy is one of the significant causes of respiratory allergies in both children and adult patients. In addition to pharmacological treatment, the cornerstone of therapy also…
31. 1. 2023 Source: Dust Mite Allergy
těžká AD u dospělého

Long-term Safety of Dupilumab in Adult Patients with Moderate to Severe Atopic Dermatitis

Moderate to severe atopic dermatitis (AD) often requires systemic therapy. The long-term safety of dupilumab in patients with this condition was evaluated in an open-label extension (OLE) of the…
24. 1. 2023 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation
nádor výzkum léčby rakoviny

Treatment of Tumors Using Ultrasound? The First Results of the Use of Histotripsy Look Promising

Histotripsy represents a new therapeutic method that allows the non-invasive removal of tumor tissue using the principle of so-called ultrasound cavitation. The method has been successfully tested in…
24. 1. 2023 Source: proLékaře.cz
senior smejko

Tiapride versus Haloperidol in the Therapy of Aggressiveness and Agitation in Elderly Patients with Cognitive Impairment

Acute restlessness, agitation, and aggression can be associated with psychiatric disorders but also be manifestations of somatic illnesses. Psychomotor agitation combined with disorientation is…
19. 1. 2023 Source: Viral infections
EKG monitor amyloid

Non-Invasive Diagnosis of Cardiac Amyloidosis

Cardiac amyloidosis has always been considered a rare pathology. However, thanks to advancements in imaging methods and laboratory tests, it is now evident that it might be responsible for a larger…
16. 1. 2023 Source: Amyloidosis
alzheimer tvář

Memantine, Acetylcholinesterase Inhibitors, and Their Combination in the Treatment of Alzheimer's Disease −⁠ Findings from Meta-Analyses

Is memantine, an acetylcholinesterase inhibitor (donepezil), or their combination more advantageous in the therapy of Alzheimer's disease? Two meta-analyses tried to answer this question, and we…
12. 1. 2023 Source: Cognitive in the treatment of Alzheimer's disease
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