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News Current findings on the treatment of gestational diabetes and DM2 in pregnancy with metformin

Recent reviews have shown that metformin is a safe alternative to insulin in the treatment of diabetes during pregnancy. For gestational diabetes (GDM) and type 2 diabetes mellitus (DM2), metformin administered to pregnant women has its benefits, but also certain risks.

Source: Modern Treatment of Diabetes 12. 3. 2024

News Barth Syndrome Has Its First Approved Therapy —⁠ For Now Only in the U.S.

The accelerated approval of elamipretide by the U.S. FDA marks a historic milestone in the treatment of mitochondrial diseases. It is the first therapy targeting cardiolipin dysfunction and the first approved drug for patients with Barth syndrome —⁠ an ultra-rare, life-threatening disorder that primarily affects boys.

Source: 26. 11. 2025

News Relationship between Thyroid Gland Echogenicity and Its Function in Pediatric Patients with Hashimoto's Thyroiditis

Hashimoto's (chronic lymphocytic) thyroiditis is the most common cause of acquired hypothyroidism in both adults and pediatric patients in developed countries. The study presented below explored the relationship between thyroid gland (TG) echogenicity observed in ultrasound (US) examinations and its function in patients diagnosed with this condition.

Source: Thyroid Disorders 22. 9. 2021

News Compression Therapy with Zinc Oxide Dressings in Dermatology

Zinc oxide dressings have a long-standing tradition and continue to find their place in modern dermatology. Compression therapy is the cornerstone of conservative treatment for chronic venous insufficiency and lymphatic insufficiency and should not be overlooked even at the stage of venous leg ulcers.

Source: Wound Healing 10. 5. 2023

News Current European Recommendations for the Treatment of Renal Colic Due to Urolithiasis

At the annual congress in Milan in 2023, new recommendations from the European Association of Urology (EAU) for the acute treatment of patients with renal colic were presented. We summarize the key points concerning primarily analgesic treatment.

Source: Analgesia 21. 6. 2024

News Incontinence as a Consequence of Surgical Procedure on the Prostate

Despite the advent of new surgical methods, urinary incontinence after prostate procedures remains a clinically significant iatrogenic complication. For patients, it represents a significant stress factor that carries physical and psychosocial consequences.

Source: Incontinence 17. 4. 2020

News Positive Effect of Pregabalin Not Only on Neuropathic Pain in Patients with Spinal Cord Injury

Spinal cord injury is often accompanied by painful conditions. A study published in the prestigious journal Neurology demonstrated that administering pregabalin to these patients can bring more than just pain relief.

Source: Neuropathic Pain 18. 2. 2020

Články časopisu Autoimmune Liver Diseases in Children. Part I

Author of the article: P. Dědek Source: Česko-slovenská pediatrie | 12/2010 13. 12. 2010

News How Diabetes Shortens Life or Mortality of Patients with Type 2 Diabetes

Type 2 diabetes mellitus (DM) has a significant impact on overall mortality across age categories. Who is most affected by this disease in terms of age and gender, and what are the current trends in mortality among the diabetic population?

Source: Diabetes 17. 2. 2022

Články časopisu Small cell lung cancer –⁠ news in the tumour´s biology

Author of the article: Klára Pavlíčková, Radoslav Matěj Source: Česko-slovenská patologie | 1/2023 18. 4. 2023

News Metamizole in Pain Therapy in the General Practitioner and Pediatric Office

Metamizole is a pyrazole analgesic-antipyretic with spasmolytic effects, indicated for the treatment of post-traumatic or postoperative pain, visceral colic, cancer pain, and high fever unresponsive to other treatments. The advantage of this drug is its good tolerance without serious adverse effects on the gastrointestinal system, no impact on platelet aggregation, and usability in adults and children of all ages.

Source: Updates in Pain Treatment 30. 3. 2023

News Oral Azacitidine Prolongs Survival of AML Patients Regardless of Measurable Residual Disease

Intensive chemotherapy for patients newly diagnosed with acute myeloid leukemia (AML) often achieves high remission rates, although these remissions are often only temporary. Consolidation therapy with azacitidine (AZA) extends post-remission survival and disease-free intervals.

Source: Acute Myeloid Leukemia 6. 6. 2023

News Analgesic Effects of Using Ringer's Solution in Wound Healing Management

Pain resulting from skin defects of various etiologies causes significant discomfort for the patient. However, wound care using Ringer's solution and the use of primary dressings, which include this solution to maintain a constant moist environment in the wound, can help address this problem.

Source: Wound Healing 25. 2. 2022

News Diosmin and Hesperidin: What Does Pharmacokinetics Show?

Flavonoids are plant-derived compounds that have a number of beneficial pharmacological effects. Among the most well-known flavonoids, alongside rutin, are diosmin and hesperidin, which are used as venotonics and vasoprotectives in chronic venous insufficiency (CVI).

Source: Venous Insufficiency 23. 4. 2020

News Odor in Incontinence is a Common Concern of Patients

Urinary incontinence represents a significant stigma, which usually deprives the affected person of all social contact, work and leisure activities, as well as intimate life. According to statistics, fears of odor contribute significantly to this isolation, almost in 40% of cases.

Source: Incontinence 9. 9. 2020