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News Dupilumab Now Covered for Atopic Dermatitis in Children Older Than 6 Years

Dupilumab is now fully covered by public health insurance for pediatric patients from 6 years old with atopic dermatitis. This opens up a new possibility for pediatric patients with this condition to improve their quality of life.

Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation 22. 1. 2022

Články časopisu Prevention of TEN in surgery, prolonged thromboprophylaxis

Author of the article: Z. Krška Source: Rozhledy v chirurgii | 5/2012 30. 5. 2012

News Current Approaches to COPD Therapy According to GOLD Recommendations and in the Conditions of Czech Practice

Chronic Obstructive Pulmonary Disease (COPD) represents a significant global cause of morbidity and mortality with a high prevalence that is expected to increase significantly in the coming years. Since it is a preventable and treatable disease, active therapy, which is globally guided by international recommendations based on the GOLD strategy, plays an important role. However, in the following article, we will also place these recommendations in the current context of care for these patients in the Czech Republic.

Source: Treatment of Asthma and COPD 15. 11. 2022

News Anticoagulants and Antiplatelets in the Treatment of Acute Coronary Syndromes

Anticoagulants and antiplatelets are a key part of the therapeutic strategies used in the treatment of acute coronary syndromes (ACS). They reduce the risk of acute and late complications, morbidity, and mortality in patients. On the other hand, their main disadvantage is the potential occurrence of bleeding complications. Therefore, the goal of physicians is to use these medications appropriately, maximizing benefits for patients while minimizing the risk of bleeding.

Source: Thromboprophylaxis 13. 6. 2022

News Current Recommendations by the ELN Expert Panel on AML Diagnosis Management

The 2022 recommendations from European LeukemiaNet (ELN) add new information to the previous recommendations from 2010 and 2017. They concern the diagnosis and treatment of acute myeloid leukemia (AML) in adults from the perspective of pathogenesis, disease classification adjustment, possibilities of genomic diagnosis, and the inclusion of minimal residual disease (MRD) assessment.

Source: Acute Myeloid Leukemia 9. 5. 2023

News Possible Uses of Desodrop in Therapy and Prevention of Ophthalmological Diseases

The medical device Desodrop is the first topical eye preparation based on ozone, intended for the prevention and therapy of eye infections and other diseases. Its efficacy and safety have been demonstrated through numerous experimental studies and clinical trials, making it a suitable alternative for topical therapy in children and adults.

Source: Treatment of Glaucoma 15. 12. 2022

News Spasmolytic Effect of Metamizole

A study aimed at clarifying the mechanism of action of metamizole suggested that the clinically proven effect of this analgesic on colicky pain originating from the biliary tract could be due to agonism on β2-adrenergic receptors in the smooth muscle of the bile ducts.

Source: Analgesia 19. 4. 2021

Články časopisu Depression in Selected Neurological Disorders

Author of the article: I. Štětkářová, J. Horáček Source: Česká a slovenská neurologie a neurochirurgie | 6/2016 10. 11. 2016

News Prescription Restrictions on Antidiabetics Authorized for Prescription by General Practitioners -⁠ Status as of October 2020

Diabetes mellitus (DM) has become an increasing problem worldwide in recent years. Long-term complications of DM lead to increased morbidity and mortality in the diabetic population, and their prevention determines the main treatment goals of DM. The treatment and management of patients with type 2 diabetes (DM2) are provided by either a general practitioner's office (GP) or a diabetology clinic. According to available data, over 200,000 patients with DM2 are currently treated and managed in GP offices.

Source: Diabetes 15. 10. 2020

News Prevalence and Manifestations of Cow Milk Protein Allergy

The prevalence of food allergies is on the rise, along with the severity and variety of their manifestations. The most common food allergy in infants and toddlers is cow milk protein allergy (CMPA).

Source: GI, colic and microbiome 20. 2. 2020

News Can we properly manage osteoporotic fractures?

Osteoporotic fractures are associated with increased morbidity and mortality and often lead to an overall deterioration in the quality of life. We should not forget to diagnose osteoporosis in patients after fractures and subsequently set appropriate therapy.

Source: Osteoporosis – Trends in Sequential Therapy 29. 2. 2024

News Possibilities of Using Metamizole in the Treatment of Acute Primary Headaches

The aim of the review article by Brazilian authors was to summarize the efficacy and safety of metamizole in the treatment of acute primary headaches, such as migraine, episodic tension-type headache (ETTH), cluster headache, and unclassified primary pain in adults and children.

Source: Analgesia 26. 10. 2020

News MD Šimon Kozák: In algology, nothing works miraculously overnight! It is important to seek advice from specialists

Why is it not advisable to rely on one method in pain treatment? What about patients with a mixed type of pain, whose numbers are increasing? And why shouldn’t surgical solutions for back pain be the method of first choice? We discuss all this and other important, current, and practical insights in the field of algology with the head of the pain treatment team at the Clinic of Anesthesiology and Resuscitation of the 3rd Faculty of Medicine, Charles University in Prague, and the University Hospital Královské Vinohrady, MD Šimon Kozák.

Source: Analgesia 21. 6. 2024

News Effectiveness of Bisoprolol in Patients with Cardiac Arrhythmias –⁠ A Systematic Review of Studies

Last year, a Franco-Romanian team published a study that conducted a systematic review of existing evidence on bisoprolol in the context of arrhythmia treatment. The authors noted that bisoprolol, like other beta-blockers (BB), is used for a variety of cardiovascular diseases, but it is not mentioned in the European Society of Cardiology (ESC) guidelines for managing patients with ventricular arrhythmias and preventing sudden cardiac death.

Source: Cardiovascular Continuum 12. 7. 2023

News What is the future of xenotransplantation? Pig liver and kidneys transplanted to humans for the first time

The initial successes of pig organ transplants to humans, conducted this March, gave hope that clinical trials of these procedures could soon become a reality. What path then leads to the clinical use of xenotransplantation?

Source: 30. 4. 2024