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Články časopisu A geriatric patient in dialysis care –⁠ experience from the Centre for post-acute care at the Motol hospital

Author of the article: M. Nováková Source: Geriatrie a Gerontologie | 1/2018 30. 3. 2018

Články časopisu Treatment of liver cirrhosis –⁠ actually possibility of ambulant internist

Author of the article: Jiří Ehrmann, Květa Aiglová, Michal Konečný, Vlastimil Procházka, Drahomíra Vrzalová Source: Vnitřní lékařství | 7-8/2016 6. 9. 2016

News Pharmacotherapy of Hip Osteoarthritis with Unsaponifiable Soy and Avocado Oil –⁠ Insights from the ERADIAS Study

Unsaponifiable soy and avocado oil is indicated for the symptomatic therapy of hip and knee osteoarthritis. Research primarily focuses on the effectiveness of the drug in patients with knee osteoarthritis; there are significantly fewer studies focused on the hip area and their results are not consistent. For this reason, an extensive study was conducted by French authors evaluating the impact of the drug on the progression of hip osteoarthritis in several hundred patients over the medium term.

Source: Osteoarthritis Therapy 27. 2. 2020

Články časopisu Skin conditions in patients with inflammatory bowel diseases

Author of the article: K. Jůzlová, M. Krásová, J. Hercogová Source: Gastroenterologie a hepatologie | 1/2017 21. 2. 2017

News Effect of Azacitidine in the Treatment of Acute Myeloid Leukemia on Long-Term Patient Survival

The work cited below presents freshly updated results from the Quazar AML-001 study evaluating azacitidine (AZA) in the treatment of acute myeloid leukemia (AML), now with a median follow-up period of 55.5 months. Among other things, clinical and biological variables predictive of long-term survival, defined here as survival ≥ 3 years from randomization within the study, were examined.

Source: Acute Myeloid Leukemia 6. 6. 2023

News Current Legislative Changes Relating to Medical Devices –⁠ Overview Summary in a Nutshell

In 2022, several legislative changes were introduced in the area of medical devices (MD) for moist wound care. We are summarizing the news from three sectors, as presented by Mgr. Jan Zahálka at the Interdisciplinary Cooperation in the Treatment of Wounds and Skin Defects congress in 2022: prescribing MD by nurses, European Union Medical Device Regulation (MDR), and the issue of MD as potential hazardous waste.

Source: Wound Healing 21. 2. 2023

News Valproate and Lithium in Maintenance Therapy of Bipolar Affective Disorder

Among the so-called mood stabilizers, drugs commonly used in the therapy of bipolar affective disorder, are valproate and lithium. Canadian authors recently conducted a post hoc analysis of a study aimed at comparing their effectiveness in the maintenance treatment of bipolar I disorder.

Source: Bipolar Disorder 8. 6. 2020

News Successful Resection of a Rectosigmoid Tumor After Long-term Induction Biochemotherapy –⁠ A Case Report

Neoadjuvant treatment (chemoradiotherapy) for colorectal cancer is regularly used in advanced rectal tumors, with the goal of reducing the tumor size for the surgeon and ensuring the best possible radical outcome for the patient. In metastatic tumors of the remaining parts of the digestive tract, we talk more about induction treatment, which uses a combination of targeted therapy and chemotherapy for the same purpose –⁠ reducing the extent of the tumor disease and possibly enabling surgery including radical removal of metastatic foci. The duration of this treatment is usually up to 6 months followed by surgery (surgeries). The following case report describes a successful surgical solution in a patient with an advanced sigmoid tumor even after more than 3 years of combination chemotherapy and targeted therapy.

Source: Colorectal Cancer 20. 6. 2022

News Effects of Progestins in Combination with EE on Endothelial Function, Lipid Levels, and Oxidative Stress in Women with Endometriosis

Studies have shown endothelial dysfunction and increased oxidative stress in women with endometriosis. Theoretically, they may be at increased cardiovascular risk. The study presented below investigated the effects of progestins with or without androgenic properties in combination with ethinylestradiol (EE) on endothelial function, lipid levels, and oxidative stress in women with endometriosis.

Source: Oral Contraception 15. 2. 2022

News “Customized Schizophrenia Treatment”: Benefits of Therapeutic Innovations in Inpatient and Outpatient Care Thanks to Gentler Antipsychotics

In the field of schizophrenia treatment, the possibility of significantly greater individualization, brought about by gentler antipsychotics, is currently a hot topic. A major focus is the differences in schizophrenia therapy during hospitalization and subsequently in outpatient care. These topics were also addressed in a seminar called “Customized Schizophrenia Treatment,” supported by Angelini, which took place in Brno.

Source: Modern Treatment of Schizophrenia 24. 5. 2023

News Dynamics of Allergy Development in Children

The prevalence of allergic diseases in children in developed countries has been steadily increasing in recent decades. Slovak authors attempted to describe the dynamics of the development of allergic symptoms in a prospective cohort of children who developed atopic dermatitis, rhinoconjunctivitis, wheezing, urticaria, or food allergy within the first 5 years of life.

Source: Allergic Reactions 1. 10. 2020

News HPD 2024: Czech data from real-world practice confirm that mucolytic treatment can reduce COPD exacerbations, even in the future

Chronic obstructive pulmonary disease (COPD) is a global issue. Does it create the same burden everywhere? How does it contribute to premature deaths? How do women cope with COPD, and what significant problem does it pose for them? What factors contribute to it not being considered solely a smoker's disease? Why is it appropriate to add mucoactive agents when trying to eliminate COPD exacerbations? What emerged from early COPD screening conducted in the Czech Republic, and what do Czech real-world data show regarding the effectiveness of erdosteine in exacerbations? And what should be included in the proper diagnosis and treatment of this disease? All these topics were covered in a lecture by the head of the Pulmonary Clinic of the Medical Faculty of Charles University and University Hospital Hradec Králové, Associate Professor Vladimír Koblížek, M.D., Ph.D., during the XXVIII Hradec Pneumology Days held from April 24-26, 2024.

Source: Cough Therapy 24. 5. 2024

News MS in Children –⁠ An Overlooked Sister of Adult Diseases?

Multiple sclerosis is not just an adult disease. How common is it in children and how have current therapeutic possibilities advanced for this population both in our country and around the world?

Source: Multiple Sclerosis 6. 6. 2022

News Metamizole as an Analgesic with a Favorable Benefit-Risk Ratio

Metamizole is a well-established and widely used molecule in many countries worldwide, suitable as an alternative to opioids for patients with moderate to severe acute or chronic pain. The popularity of this drug is associated not only with its efficacy but also with its safety, with no contraindications for patients with cardiovascular, renal, or gastrointestinal comorbidities.

Source: Analgesia 29. 3. 2023

News Safety and Efficacy of Negative Pressure Therapy in Acute Infected Wounds

Negative Pressure Wound Therapy (NPWT) is a globally widespread wound care method. It involves creating a local negative pressure in the wound, with key benefits including moist wound healing in a closed environment, gradual reduction of wound volume by drawing in the edges, continuous drainage of exudate and tissue fluid, and promotion of granulation.

Source: Wound Healing 4. 5. 2020