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Články časopisu Hand osteoarthritis

Author of the article: prof. MUDr. Ph.D. Ladislav Šenolt Source: Časopis lékařů českých | 6/2016 9. 11. 2016

News Possibilities of Using Metamizole in the Treatment of Acute Primary Headaches

The aim of the review article by Brazilian authors was to summarize the efficacy and safety of metamizole in the treatment of acute primary headaches, such as migraine, episodic tension-type headache (ETTH), cluster headache, and unclassified primary pain in adults and children.

Source: Analgesia 26. 10. 2020

News Trazodone as an Effective Medicine in the Therapy of Depression and Insomnia

Trazodone (Trittico®) is a medicine indicated for the treatment of depression, which has also been shown to have a positive effect in treating other associated conditions. In practice, however, the potential of its multimodal effect sometimes remains untapped.

Source: Depression and Anxiety 19. 7. 2020

Články časopisu Clinical nutrition in surgery –⁠ ESPEN guideline with consensual voting of the working group of Society of Clinical Nutrition and Intensive Metabolic Care (SKVIMP

Author of the article: I. Satinský, E. Havel, K. Bezděk, I. Hanke, M. Káňová, P. Kohout, J. Maňák, V. Maňásek, J. Matek, F. Novák, I. Novák, M. Oliverius, J. Poledník, M. Šenkyřík, Z. Šerclová, P. Tešínský, L. Urbánek, Z. Zadák Source: Anesteziologie a intenzivní medicína | 2/2019 13. 5. 2019

News Targeting HER2 is Clinically Meaningful Even with Its Low Expression

Distinguishing HER2 receptor expression status on the surface of breast cancer tumor cells as simply positive or negative is now proving insufficient. Ultimately, it can lead to the non-administration of effective targeted therapy. What do we actually know about the “gray zone” between HER2 positivity and negativity?

Source: Ovarian and Breast Cancer 22. 5. 2024

News Diagnosis and Management of Interstitial Lung Processes Associated with Rheumatoid Arthritis

Interstitial lung processes (ILD) are common yet insufficiently diagnosed complications of rheumatoid arthritis (RA), significantly increasing the morbidity and mortality of patients. ILD can occur at any stage of RA, presenting a diverse clinical picture. Usual interstitial pneumonia (UIP) and nonspecific interstitial pneumonia (NSIP) are the most common findings on high-resolution CT (HRCT). Some patients with RA-associated ILD may exhibit a progressive phenotype characterized by expanding fibrotic changes on HRCT, declining lung function, worsening respiratory symptoms, and early mortality. A recently published review summarizes strategies for screening, monitoring, and managing ILD in RA.

Source: Progressive Interstitial Pulmonary Processes 3. 1. 2024

News Desirable Side Effects of Antidiabetics

The days when diabetology was a field solely focused on normalizing blood sugar levels are long gone. Today, the approach in diabetology increasingly prioritizes influencing the patient's overall life prognosis, particularly reducing cardiovascular risk. What can be the desirable side effects of the main groups of antidiabetics that are not related to merely lowering glucose levels?

Source: Diabetes 6. 11. 2020

News How to Set Individual Treatment Goals for Type 2 Diabetes?

Treatment goals for type 2 diabetes should always be set individually. In practice, this mainly involves an indicator of the success of long-term compensation –⁠ glycated hemoglobin (HbA_1c). Recommendations for the diagnosis and treatment of diabetes for general practitioners from 2020 list different target HbA_1c values according to the risk of hypoglycemia and other parameters. They also recall different target values for fit, frail, and dependent seniors.

Source: Diabetes 28. 8. 2020

Články časopisu Neonatal seizures –⁠ current view of the issue

Author of the article: K. Španělová, K. Česká, H. Ošlejšková, Š. Aulická Source: Česká a slovenská neurologie a neurochirurgie | 1/2020 5. 2. 2020

Články časopisu Prospects for the treatment of osteoarthritis

Author of the article: K. Pavelka Source: Česká revmatologie | 1/2015 5. 3. 2015

News How to Properly Treat Frostbite?

Frostbite, or congelation, is defined as an acute condition involving damage to the skin and subcutaneous tissues due to local cold, particularly at subzero temperatures. Treatment requires quality care. By choosing the right therapy, we can prevent complications that might otherwise threaten the patient with amputation of the affected part. The healing process is lengthy and requires patience from both the patient and the attending physician.

Source: Wound Healing 7. 12. 2021

News Ocrelizumab in the treatment of multiple sclerosis in real-world practice –⁠ a systematic review of published studies

In controlled study programs, ocrelizumab has demonstrated beneficial effects on improving clinical parameters in patients with multiple sclerosis, such as the annual relapse rate or confirmed disability progression. However, to get a complete picture of its clinical benefit, real-world evidence in a broad patient population is also needed. A systematic review of real-world clinical practice studies with ocrelizumab, published in March 2023, demonstrates its benefits in patients with relapsing-remitting multiple sclerosis (RRMS) and primary progressive multiple sclerosis (PPMS) in terms of relapse frequency, disease activity on MRI, disability, absence of disease activity (NEDA), and quality of life.

Source: Neurology - Multiple Sclerosis 27. 9. 2023

Články časopisu Comorbidities of Alzheimer‘s disease –⁠ results of a multicentric observational COSMOS study in the Slovak Republic

Author of the article: M. Minár, J. Dragašek, I. Mátéffy, P. Valkovič Source: Česká a slovenská neurologie a neurochirurgie | 1/2020 5. 2. 2020

Články časopisu A Notice on Classification, Terminology and Contents Innovations to the Primary Headaches Section of the International Classification of Headache Disorders (ICHD-3 Beta)

Author of the article: J. Opavský Source: Česká a slovenská neurologie a neurochirurgie | 1/2014 28. 1. 2014

Články časopisu Possible prevention of Alzheimer’s disease

Author of the article: J. Janoutová, M. Kovalová, P. Ambroz, O. Machaczka, A. Zatloukalová, K. Němček, E. Mrázková, O. Košta, D. Školoudík, V. Janout Source: Česká a slovenská neurologie a neurochirurgie | 1/2020 5. 2. 2020