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News How to Save a Leg from Amputation?

Feared complications in diabetics include defects in typical locations on the lower limbs. Their presence and frequent recurrences increase the risk of possible amputation of varying degrees, mainly depending on the involvement of deep structures, i.e., tendons, joint capsules, joints, and bones. How can this scenario be avoided? One answer might be HydroTherapy.

Source: Wound Healing 10. 8. 2022

News Idiopathic Pulmonary Fibrosis: Rare Disease with Severe Prognosis

Idiopathic pulmonary fibrosis (IPF) represents a diagnostic and therapeutic challenge. This rare diffuse primary fibroproliferative involvement of lung tissue is characterized by progressive exertional dyspnea, with antifibrotic treatment being the first-line therapeutic modality.

Source: Pulmonary Fibrosis 14. 4. 2020

Články časopisu Can affecting of subchondral bone slow the progression of osteoarthritis?

Author of the article: Pavelka Karel Source: Clinical Osteology | 2/2019 2. 9. 2019

News When to Consider Gaucher Disease and How to Diagnose It Early and Correctly

Considering Gaucher disease (GD) as a cause of a patient's problems, especially in the case of splenomegaly and bleeding manifestations, is very important, regardless of age. Screening using the dry blood spot method is available and very simple.

Source: Rare Diseases in Hematology 16. 5. 2023

News Polatuzumab Vedotin in the Treatment of NHL -⁠ News from the 25th EHA Congress

Polatuzumab vedotin (Polivy) is approved in the EU for the treatment of patients with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL), for whom hematopoietic stem cell transplantation (HSCT) is not suitable. We provide an overview of the latest news regarding the role of this modern medicine in the therapy of non-Hodgkin's lymphomas (NHL), presented at the 25th Congress of the European Hematology Association (EHA), held virtually due to the pandemic situation.

Source: Non-Hodgkin Lymphomas and CLL 29. 9. 2020

News Domestic application of biological asthma treatment improves quality of life and reduces doctor visits

The benefits of the possibility of home application of omalizumab, a monoclonal antibody indicated for patients with severe allergic asthma, are summarized by Dr. Jakub Novosad, Ph.D., from the Institute of Clinical Immunology and Allergology, Charles University Medical Faculty and University Hospital Hradec Králové.

Source: Asthma under control 9. 4. 2020

Články časopisu Obesity and its influence on sexual dysfunctions

Author of the article: Dita Pichlerová, Jitka Herlesová, Petr Weiss Source: Praktická gynekologie | 2/2013 1. 5. 2013

News Alternative to benzodiazepines or clomethiazole in the treatment of alcohol withdrawal syndrome?

Alcohol withdrawal syndrome (AWS) is a potentially life-threatening condition. A meta-analysis published in the journal Pharmacopsychiatry in September 2019 examines the effect of the combination of tiapridal and carbamazepine in the treatment of AWS. Is this combination a viable alternative to benzodiazepines or clomethiazole?

Source: Geriatric Patient 20. 3. 2020

News Levodropropizine –⁠ a non-codeine antitussive with minimal side effects, contraindications, and drug interactions

For symptomatic treatment of dry, irritating, and exhausting cough, both codeine and non-codeine antitussives can be used. One of the non-codeine antitussives is levodropropizine. Its antitussive effect is comparable to centrally acting codeine antitussives, but with a significantly lower incidence of side effects. Compared to codeine, it has a much narrower range of contraindications, and no interactions with benzodiazepines or drugs used in the treatment of bronchopulmonary diseases have been observed.

Source: Cough Therapy 10. 1. 2022

Články časopisu Primary immunodeficiencies in adults

Author of the article: Jiří Litzman Source: Vnitřní lékařství | 2/2019 15. 3. 2019

News Memantine and Donepezil –⁠ Unity is Strength

Memantine and donepezil are both used in the therapy of Alzheimer's disease (AD). However, how does the combination of these drugs fare in the treatment of moderate to severe AD?

Source: Cognitive in the treatment of Alzheimer's disease 12. 10. 2020

News Hybrid Cooperating Complexes in Osteoarthritis Treatment

Intra-articular application of corticosteroids and hyaluronic acid is part of the treatment of osteoarthritis (OA) in patients for whom oral or topical treatment does not provide sufficient response. The following text addresses the lubricating and protective properties of synovial fluid and the associated choice of suitable intra-articular viscosupplementation, with an emphasis on innovative molecules with high concentrations of hyaluronic acid and low viscosity.

Source: Pain Management 21. 6. 2024