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News Levodropropizine vs. dextromethorphan: Which one to recommend to your patients and why?

Reducing cough intensity and nighttime awakenings, rapid onset of action, simple dosing regimen, and good treatment tolerance—these are the properties we expect from antitussive drugs, not only in pediatrics. So which of these wins in these parameters compared to other commonly used over-the-counter antitussives?

Source: Cough Therapy 12. 11. 2020

Články časopisu Type 2 diabetes mellitus in old age

Author of the article: MUDr. Martina Lášticová Source: Geriatrie a Gerontologie | 2/2014 26. 6. 2014

News Prophylaxis with Enoxaparin After Total Knee or Hip Replacement

Venous thromboembolic disease is a significant cause of complications in surgical patients during and after hospitalization. The authors of a recently published Portuguese observational study evaluated the incidence of complications with prophylaxis using low-molecular-weight heparin (LMWH) enoxaparin in a population after hip or knee joint replacement.

Source: Thromboprophylaxis 28. 11. 2023

Články časopisu Cholesterol metabolism disturbances and statin therapy in elderly patients

Author of the article: P. Vyroubal Source: Geriatrie a Gerontologie | 2/2013 1. 5. 2013

News Metamizole vs. Tramadol in Postoperative Analgesia

Metamizole and tramadol are well-known analgesics that have been used in practice for a long time. Interesting insights into these substances were provided by the studies presented below. Spanish doctors evaluated the efficacy and safety of metamizole compared to tramadol in postoperative analgesia after abdominal hysterectomy. German researchers were interested in the possibility of applying a combination of these drugs in an analgesic regime controlled by the patient.

Source: Analgesia 19. 4. 2021

Články časopisu HELLP syndrome complicated by liver rupture –⁠ case report

Author of the article: M. Součková, R. Pilka, T. Malý, M. Procházka, J. Frančáková, V. Lattová, K. Horváthová Source: Česká gynekologie | 3/2014 18. 6. 2014

News Fibrinogen and Management of Peripartum Life-Threatening Hemorrhage

The most common cause of maternal death in the developed world continues to be peripartum life-threatening hemorrhage. It can result as a consequence of the consumption of coagulation factors, primarily fibrinogen. The analysis presented below summarizes information on the prevention of this complication and the use of fibrinogen concentrate therapy.

Source: Life-threatening Bleeding 15. 6. 2022

News Current Therapy Options for Interstitial Lung Diseases

Interstitial lung diseases (ILDs) represent a heterogeneous group of disorders characterized by inflammatory or fibrotic changes in the lung parenchyma. Simply put, they can be divided into inflammatory and fibrotic, with inflammatory ILDs often progressing to a fibrotic stage. Interstitial lung diseases are also associated with high morbidity and early mortality. The following text briefly summarizes the current recommendations regarding the therapy for these diseases.

Source: Progressive Interstitial Pulmonary Processes 29. 8. 2022

News Current Recommendations of the International League Against Epilepsy for the Treatment of Seizures in Newborns

In 2023, a team of experts in neurology, neonatology, and pediatrics, along with representatives of parents, published recommendations for the treatment of epileptic seizures in newborns. These were developed based on a systematic literature review (and in cases of insufficient evidence, based on consensus achieved using the Delphi method) and include first and second choice pharmacotherapy, dosing, duration of treatment, effects of therapeutic hypothermia, and the use of pyridoxine. We offer their summary in a nutshell (and always indicate the strength of the recommendation in parentheses).

Source: Quick aid for acute convulsive seizures in children and adolescents 21. 5. 2024

Články časopisu Vascular age

Author of the article: Ondřej Petrák, Richard Češka Source: Vnitřní lékařství | 12/2019 19. 1. 2020

News Comorbidities of Migraine and Their Impact on Pain Frequency and Intensity

The MAST study, published in March of this year in the prestigious The Journal of Headache and Pain, focused on the occurrence of associated diseases in patients with migraine. What is the prevalence of individual comorbidities and which of them are associated with changes in pain intensity and frequency?

Source: Migraine 27. 7. 2020

News X-ray in Dentistry: Who Can Indicate and Who Can Perform?

X-ray is an integral and important part of dental diagnostics. However, since it is also a source of ionizing radiation, its use is subject to legislative regulations that govern it.

Source: Dental Care 4. 6. 2024

Články časopisu Bone cement implantation syndrome

Author of the article: Filip Čechlovský Source: Úrazová chirurgie | 2/2017 17. 5. 2018

News When to Suspect Dravet Syndrome?

In 2022, an international consensus panel of experts on the diagnosis and treatment of Dravet syndrome was published. This was created due to the recently approved specific treatments for this disease and the development of disease-modifying therapies. The goal of the consensus is to improve diagnosis, set therapeutic goals, and optimal treatment procedures. We summarize the symptoms of the disease and situations in which genetic testing of the causal mutation is appropriate.

Source: Rare Diseases in Neurology 29. 6. 2023

News Initial Treatment for Newly Diagnosed ITP Patients at a Glance

The revised international consensus on the management of primary immune thrombocytopenia (ITP) from 2019 outlines several points summarizing suitable initial treatment for newly diagnosed individuals with ITP.

Source: Immune Thrombocytopenia 21. 2. 2023