Current view of the effect of hormone replacement therapy on cardiovascular risks – 2007 update
Authors:
T. Fait
Authors‘ workplace:
Gynekologicko–porodnická klinika 1. LF UK
a VFN Praha
Published in:
Prakt Gyn 2007; 11(5): 223-225
Overview
The reanalysis of WHI along age subgroups has confirmed that early start of hormone replacement therapy has neutral of moderate beneficial influence on the cardiovascular system.
Key words:
hormone replacement therapy – cardiovascular risk – therapeutic window
Sources
1. Writing Group for the Women´s Health Initiative Investigators. JAMA 2002; 288: 321-333.
2. WHI Steering Commitee. Effect of CEE in postmenopausal women. JAMA 2004; 291: 1701-1712.
3. Salpetr SR, Walsh JME, Greyber E et al. Mortality associated with hormone replacement therapy in younger and older women. J Gen Intern Med 2004; 19: 791-804.
4. Rossouw JER, Prentice RL, Manson JE et al. Postmenopausal hormone therapy and risk of cardiovascular diseae by age and years since menopause. JAMA 2007; 297(13): 1465-1477.
5. Genazzani AR, Gambacciani M, Simoncini T. The lates elaboration of the WHI data on and cardiovascular data in postmenopausal women. Gynecol Endocrinol 2007; 23(4): 183-185.
6. Depypere HT, Tummers P, Bacquer et al. Number of women needed in a prospektive trial to prove potential benfit of hormone replacement therapy. Climacteric 2997; 10: 238-243.
7. Manson JE, Allison MA, Rossouw JE et al. Estrogen therapy and coronary-artery kalcification. NEJM 2007; 356: 2591-2602.
8. Collins P, Rosano G, Casey C et al. Management of cardiovascular risk in the peri-menopausal women: a consensus statement of European cardiologists and gynaecologists. European Heart Journal 2007; 28: 2028-2040.
Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Practical Gynecology
2007 Issue 5
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