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Advantages of Non-invasive Diagnostics of Foetal Anaemia – Case Report


Authors: R. Doubek;  D. Petrovová;  R. Gerychová;  J. Zahradníčková 1
Authors‘ workplace: Gynekologicko-porodnická klinika LF MU a FN Brno ;  Novorozenecké oddělení LF MU a FN Brno 1
Published in: Prakt Gyn 2005; 9(5): 10-12
Category: Case Report

Overview

Objective:
Demonstration of benefit of Doppler examination of maximum flow rate in arteria cerebri media of foetus to the diagnostics of foetal anaemia in a risk patient.

Name and address of the department:
Department of Gynaecology and Obstetrics of Faculty of Medicine of Masaryk University and Faculty Hospital Brno, Czech Republic.

Case report:
36-year old patient with risk history of progression of isoimmunisation upon the invasive diagnostics of degree of foetal anaemia in previous pregnancy (mors neonati, hydrops). In the present pregnancy – with a high positive anti-erythrocyte antibodies titre – we pursued a monitoring of the disease stage through measurements of maximum flow rate in arteria cerebri media of foetus. With this approach, we succeeded to reach the 34th week of pregnancy with a good prognosis for the new-born child. Pregnancy was terminated on the ground of an indication of progressive hypertension with superimposed preeclampsia and poorly controlled gestation diabetes.

Conclusion:
In the case described, we confirmed a high accuracy of Doppler ultrasound examination in the diagnostics of foetal anaemia taking an advantage of non-invasiveness of this technique.

Key words:
isoimmunisation, foetal anaemia, Doppler, maximum flow rate, arteria cerebri media


Sources

1. Avery GB, Fletcher MA, MacDonald MG et al. Neonatology (Pathophysiology and Management of the Newborn). Philadelphia: Lippincott-Raven Pubs 1994.

2. Čech E, Hájek Z, Maršál K et al. Porodnictví. Praha: Grada Publishing 1999.

3. Detti L, Mari G. Noninvasive diagnosis of fetal anemia. Clin Obstet Gynecol 2003; 46: 923-930.

4. Gagnon R, Van den Hof M. Utilisation du doppler foetal en obstétrique. Obstet Gynaecol Can 2003; 25(7): 608-614.

5. Lubušký M, Procházka M, Šantavý J et al. Dopplerometrie při posouzení fetální anémie. Čes Gynekol 2004; 4: 316-319.

6. Stefos T, Cosmi E, Detti L et al. Correction of fetal anemia on the modele cerebral artery peak systolic velocity. Obstet Gynecol 2002; 99: 211-215.

7. Moise KJ jr. Management of Rhesus Alloimmunization in Pregnancy. Obstet Gynecol 2002; 100(4): 833.

Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
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