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Wernicke´s encephalopathy as rare complication after sleeve gastrectomy


Authors: I. Šimonik 1;  J. Bonaventura 2;  J. Tvarůžek 1;  M. Slámová 3
Authors‘ workplace: Chirurgické oddělení, Nemocnice sv. Zdislavy, a. s., Velké Meziříčí 1;  Anesteziologicko-resuscitační oddělení, Nemocnice sv. Zdislavy, a. s., Velké Meziříčí 2;  Radiologické oddělení, Nemocnice Nové Město na Moravě 3
Published in: Rozhl. Chir., 2019, roč. 98, č. 2, s. 66-70.
Category: Case Report

Overview

The authors report a case study of a 24-year-old female patient after sleeve gastrectomy with subsequent manifestation of Wernicke’s encephalopa­thy. After 5 weeks following the surgery, which were uneventful, the patient was repeatedly hospitalized in the surgical department for extreme vomiting; however, her health status rapidly improved with infusion therapy followed by careful re-alimentation. At the same time, her GIT was closely examined without any clear finding. Problems progressively deteriorated into neurological manifestations. The final diagnosis was established by MR imaging of the brain. In addition, the patient’s condition was complicated by sudden febrile status with elevated CRP values; therefore, with regard to the unclear CT finding in the abdominal cavity, a laparoscopic revision was made 8 weeks after the primary surgery. The patient survived thanks to the final correct diagnosis and administration of adequate therapy in the form of thiamine substitution. After 30 days following the last admission, the patient was discharged for home treatment in a satisfactory health condition. The aim of the case study is to describe the onset of atypical symptoms in a patient following bariatric surgery – particularly from the point of view of a surgeon – and difficult and prolonged diagnosis of this syndrome due to its relative rarity, also from the point of view of other colleagues with various specializations who participated in the establishment of the diagnostics.

Keywords:

obesity – bariatry – sleeve gastrectomy – Wernicke’s encephalopathy – Thiamine


Sources
  1. Vodička M. Wernickeova encefalopatie. Neurologie pro praxi 2015;16:360−4.

  2. Harper CG, Gles M, Finlay-Jones R. Clinical signs in the Wernicke-Korsakoff complex: a retrospective analysis of 131 cases diagnosed at necropsy. J Neurol Neurosurg Psychiatry 1986;49:341−5.

  3. Sechi G., Serra A. Wernicke’s encephalopathy: new clinical settings and recent advances in diagnosis and management. Lancet Neurol 2007;6:442−5.

  4. Debopam S. Thiamine deficiency after laparoscopic sleeve gastrectomy. Journal of Pediatric Neurosciences. 2015;10:297−9.

  5. Lingford-Hughes AR, Welch S, Nutt DJ. Evidence based guidelines for the pharmacological management of substance misuse, addition and comorbidity reco­mmendation from the British Association for Psychopharmacology. J Psychofarmacol 2004;18:293−335.

  6. Cook CC. Prevention and treatment of Wernicke-Korsakoff syndrome. Alcohol, Alcohol Suppl. 2000;35:19−20.

  7. Thompson AD, Cook CC, Touguet R, et al. The Royal College of Physicians report on alcohol: guidelines for managing Wernicke´s encephalopathy in the accident and emergency department. Alcohol, Alcohol Suppl. 2002;37:513−21.

  8. Donnino MW, Vega J, Miller J, et al. Myths and misconception of Wernicke´s encephalopathy: what every emergency physician should know. Ann Emergency Med 2007;50:715−21.

  9. Brown LM, Rowe AE, Ryle PR, et al. Efficacy of vitamin supplementation in chronic alcoholics undergoing detoxification. Alcohol Alcohol Suppl. 1983,18:18:157−66

  10. Fattal-Valevski A et al. Outbreak of life threatening thiamine deficiency in infants in Israel caused by a defective soy-based formula. Pediatrics 2005;115:233−8.

  11. Flynn A, Macaluso M, Troutman M. Wernicke´s encephalopathy: increasing clinician awareness of this serious, enigmatic, yet treatable disease. Prim Care Companion CNS Disord 2015. Available from: doi: 10.4088/PCC.14r01738.

  12. Dervaux A, Lequeille X. Le traitement par thiamine (vitamine B1) dans l’alcoolodépendance. La Presse Médicale 2017;46, Part 1:165−71.

  13. Nishimoto A, Usery J, Twilla J High-dose parenteral Thiamine in treatment of Wernicke´s encephalopathy: Case series and review of the literature. Online 2017. Available from: doi:/ invio. 11034.

  14. Isselbacher KJ, Braunwald E, Wilson JD. Harrison´s principles of internal medicine, Thirteen Edition New York McGraw-Hill 1994;1406:1156−67

  15. Davis HE, Icker GC. Clinical chemistry of thiamine. Adv Clin Chem 1983;17:93−140.

  16. Zhao R, Goldman ID. Folate and Thiamin transporters mediated by facilitative carriers SSLC19A1-3 and SLC46A1 and folate receptors. Mol. Aspects Med 2013;34:373−87.

  17. Ozand PT, Gascon GGG, Al Essa M, et al. Biotin-responsive basal ganglia disease: a novel entity. Brain: a journal of neurology, 1998;121:1267−79.

  18. Tabarki B. Biotin-responsive basal ganglia disease revisited. Clinical, radiologic a genetic findings. Neurology 2013;80:261−7.http://igor.simonik@mediterra.cz

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