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Hepatic pseudolymphoma: a surprising finding in a case with suspected generalisation of lung cancer


Authors: J. Rosendorf 1,2;  H. Mírka 3;  L. Boudová 4;  V. Liška 1,2;  V. Třeška 1
Authors‘ workplace: Chirurgická klinika Fakultní nemocnice Plzeň a Lékařská fakulta v Plzni, Univerzita Karlova 1;  Biomedicínské centrum Lékařské fakulty v Plzni, Univerzita Karlova 2;  Klinika zobrazovacích metod Fakultní nemocnice Plzeň, Lékařská fakulta v Plzni, Univerzita Karlova 3;  Šiklův ústav patologie Fakultní nemocnice Plzeň a Lékařská fakulta v Plzni, Univerzita Karlova 4
Published in: Rozhl. Chir., 2019, roč. 98, č. 11, s. 469-472.
Category: Case Report
doi: https://doi.org/10.33699/PIS.2019.98.11.469–472

Overview

Introduction: Pseudolymphoma is a rare focal lesion which occurs in different locations. Only about 50 cases of liver pseudolymphoma have been reported so far. The diagnostic process is challenging. The lesion can resemble different malignancies using various imaging methods. No typical laboratory markers are available. The right diagnosis is usually made on the basis of histological examination.

Case report: A 67 years old female patient with lung fibrosis was undergoing assessments for a malignant-appearing focal lesion of the left lung and a focal liver lesion of unknown etiology.

Upper lobectomy of the left lung proved lung carcinoma. The liver lesion was suspected for being metastatic, therefore a liver resection followed. The biopsy revealed hepatic pseudolymphoma. It took 150 days from the first positive CT scan until the liver resection. Currently, the patient shows no signs of recurrence.

Conclusion: Hepatic pseudolymphoma is a rare disease and we have only little experience with it so far. The diagnostic process is challenging, which is clear from the presented case. Only histological and immunohistochemical examinations ruled out a malignancy. A long-term observation of the patient is indicated.

Keywords:

liver – liver surgery – pseudolymphoma – reactive lymphoid hyperplasia of the liver – liver tumours


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