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Idiopathic inflammatory bowel disease – advancements in surgical treatment


Authors: J. Ulrych;  Z. Krška
Authors‘ workplace: I. chirurgická klinika 1. LF UK a VFN v Praze, přednosta: prof. MUDr. Z. Krška, CSc.
Published in: Rozhl. Chir., 2012, roč. 91, č. 10, s. 539-544.
Category: Original articles

Overview

Introduction:
Treatment of idiopathic inflammatory bowel disease is constantly developing. Biological therapy has become a standard part of conservative treatment, and gene and cell therapy of these diseases is in preclinical phase. Surgical therapy also offers some progress in the treatment, such as the increasingly preferred laparoscopic approach offering the numerous benefits of minimally invasive surgery or a tendency to perform stapled anastomosis.

Material and methods:
A retrospective analysis of patients with a diagnosis of idiopathic inflammatory bowel operated on at the First Department of Surgery, General University Hospital in the years 2007–2011 was performed.

Results:
Within this period, 179 patients diagnosed with Crohn’s disease were operated on. 30 patients underwent acute operation and 149 patients were indicated for elective surgery. In the same period, 40 patients with ulcerative colitis were indicated for surgery, of whom 22 patients for acute surgery and 18 for elective surgery.

Conclusion:
Multidisciplinary approach in the treatment of patients with inflammatory bowel disease is crucial and patients should be treated in specialized centres. New possibilities of conservative treatment and progress in surgical therapy mutually correlate, and thus the choice of a correct therapeutic procedure requires specific cooperation between the surgeon and the gastroenterologist.

Key words:
Crohn’s disease – ulcerative colitis – surgery


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