#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Gastric Carcinoma and Current Situation


Authors: J. Tesař;  Z. Krška;  M. Zeman
Authors‘ workplace: I. chirurgická klinika BHÚ VFN, Praha, přednosta: prof. MUDr. Z. Krška, CSc.
Published in: Rozhl. Chir., 2010, roč. 89, č. 3, s. 169-177.
Category: Monothematic special - Original

Overview

Introduction:
Gastric carcinoma is a serious malignant disease, manifesting often in advanced stages and with a presence of metastatic dissemination into lymph nodes.

Aim:
The aim of the study was to asses own results with a reference on modern trends in surgery of gastric carcinoma and research of dependence of the age and stage of the disease on survival.

Methods:
In the Ist Surgical Clinic of Abdominal, Thoracal and Trauma Surgery of General Teaching Hospital in Prague a total of 191 patients with gastric carcinoma were operated during a period of 10 years, from October 1998 to October 2008. To the closing date of the study 130 patients deceased, 40 patients lived on. Every patient underwent an endoscopical examination of gastroduodenum once a year. A data from 21 patients couldn’t be collected because of a bad compliance. There were 88 patients older than 65 years, 82 patients were younger. In prospective-retrospective study we examined survival of patients and dependence on age and stage of the disease.

Results and conclusion:
Total survival rate 24% corresponds with data in literature, quoted from 10 to 30%. An age isn’t an independent factor of survival. A dependence on the stage of the disease is noticeable.

Key words:
gastric carcinoma – surgical treatment – age – survival


Sources

1. Santoro, R., Carboni, F., Lepiane, P., Ettorre, G. M., Santoro, E. Clinicopathological features and prognosis of gastric cancer in young European adults. Br. J. Surg., 2007, Jun; 94(6): 737–742.

2. Ly, Q. P., Sasson, A. R. Modern surgical considerations for gastric cancer. J. Natl. Compr. Canc. Netw., 2008, Oct; 6(9): 885–894.

3. Volpe, C. M., Driscoll, D. L., Douglass, H. O. Jr. Outcome of patients with proximal gastric cancer depends on extent of resection and number of resected lymph nodes. Ann. Surg. Oncol., 2000, Mar; 7(2): 139–144.

4. Topaloglu, U., Dulundu, E., Ozkan, E., Kayahan, M., Ozel, Y. Extended lymphadenectomy for gastric cancer: a single center experience in Istanbul. Hepatogastroenterology, 2009, Jan-Feb; 56(89): 266–269.

5. Di Martino, N, Izzo, G, Cosenza, A., Vicenzo, L., Monaco, L., Torelli, F., Basciotti, A., Brillantino, A., Marra, A. Total gastrectomy for gastric cancer: can the type of lymphadenectomy condition the long-term results? Suppl. Tumori, 2005 May-Jun; 4(3): S84–S85.

6. Okajima, K., Isozaki, H. Splenectomy for treatment of gastric cancer: Japanese experience. World J. Surg., 1995, Jul-Aug; 19(4): 537–540.

7. Mönig, S. P., Collet, P. H., Baldus, S. E., Schmackpfeffer, K., Schröder, W., Thiele, J., Dienes, H. P., Hölscher, A. H. Splenectomy in proximal gastric cancer: frequency of lymph node metastasis to the splenic hilus. J. Surg. Oncol., 2001, Feb; 76(2): 89–92.

8. Yamamoto, M., Baba, H., Kakeji, Y., Endo, K., Ikeda, Y., Toh, Y., Kohnoe, S., Okamura, T., Maehara, Y. Postoperative morbidity/mortality and survival rates after total gastrectomy, with splenectomy/pancreaticosplenectomy for patients with advanced gastric cancer. Hepatogastroenterology, 2004, Jan-Feb; 51(55): 298–302.

9. Wike, H., Preussner, P., Fink, U. New developments in the treatment of gastric carcinoma. Sem. Oncol., 17, 1999, 61–70.

10. Žaloudík, J. Karcinomy trávícího traktu. Forum Medicinae, 1, 2000, 38–48.

11. Smith, J. K., McPhee, J. T., Hill, J. S., Whalen, G. F., Sullivan, M. E., Litwin, D. E., Anderson, F. A., Tseng, J. F. National outcomes after gastric resection for neoplasm. Arch. Surg., 2007, Apr; 142(4): 387–393.

12. Orsenigo, E., Tomajer, V., Palo, S. D., Carlucci, M., Vignali, A., Tamburini, A., Staudacher, C. Impact of age on postoperative outcomes in 1118 gastric cancer patients undergoing surgical treatment. Gastric Cancer, 2007; 10(1): 39–44. Epub 2007 Feb 23.

13. Saidi, R. F., Bell, J. L., Dudrick, P. S. Surgical resection for gastric cancer in elderly patients: is there a difference in outcome? J. Surg. Res., 2004, May 1; 118(1): 15–20.

14. Schwarz, R. E., Karpeh, M. S., Brennan, M. F. Factors predicting hospitalization after operative treatment for gastric carcinoma in patients older than 70 years. J. Am. Coll. Surg., 1997, Jan; 184(1): 9–15.

15. Carboni, F., Lepiane, P., Ettorre, G. M., Santoro, E. Clinicopathological features and prognosis of gastric cancer in young European adults. Br. J. Surg., 2007, Jun; 94(6): 737–742.

16. Medina-Franco, H., Heslin, M. J., Cortes-Gonzalez, R. Clinicopathological characteristics of gastric carcinoma in young and elderly patients: a comparative study. Ann. Surg. Oncol., 2000, Aug; 7(7): 515–519.

17. Stefanová, M. Epidemiologie, screening, současná diagnostika a staging karcinomu žaludku. Bulletin HPB, 2008.

18. Šimša, J. Karcinom žaludku, lymfadenektomie a detekce sentinelové uzliny. Jessenius Maxdorf, 2006.

19. Konečný, M., Geryk, E., Kubíček, P. et al. Prevalence nádorů v České Republice, 1989-2005-2015. PF Masarykovy Univerzity, Brno, 2008.

20. Bertuccio, P., Chatenoud, L., Levi, F., Praud, D., Ferlay, J., Negri, E., Malvezzi, M., La Vecchia, C. Recent patterns in gastric cancer: A global overview. Int. J. Cancer, 2009, Aug 1; 125(3): 666–673. Int J Cancer, 2009 Aug 1; 125(3): 666–673.

21. Roder, D. M. The epidemiology of gastric cancer. Gastric Cancer, 2002; 5 Suppl. 1: 5–11.

22. Šváb, J., et al. Chirurgie vyššího věku. Grada Publishing, Praha, 2008.

Labels
Surgery Orthopaedics Trauma surgery
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#