#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Patient Survival Following Radiofrequency Ablation of Liver Metastases from Colorectal Cancer


Authors: L. Starý;  I. Klementa;  P. Zbořil;  P. Skalický;  Č. Neoral
Authors‘ workplace: I. chirurgická klinika LF UP a FN Olomouc, přednosta: doc. MUDr. Č. Neoral, CSc.
Published in: Rozhl. Chir., 2010, roč. 89, č. 12, s. 780-783.
Category: Monothematic special - Original

Overview

Objective:
The objective of the work was to evaluate five-year survival rates of patients with liver metastases from colorectal cancer following radiofrequency ablation (RFA).

Material a method:
The authors prospectively evaluated a set of 32 patients indicated for radiofrequency ablation.

Results:
Patients who were indicated for RFA and for a combination of liver resection with RFA for metastasis from colorectal cancer had a one-year, three-year and five-year survival of 81%, 31% and 13%, respectively. Therefore 10 patients survived 3 years following the procedure and of these 4 obtained five-year survival.

Conclusion:
Radiofrequency ablation has become a generally accepted technique in the treatment of liver metastases. It is indicated in cases of lesions unsuitable for surgical resection, either due to large number and location or in patients with comorbidites where an extensive resection is contraindicated. Radiofrequency ablation has minimal complications and is considered on the borderline between a palliative and radical procedure.

Key words:
radiofrequency ablation – liver metastases


Sources

1. Ahmad, A., Chen, S. L., Kavanagh, M. A., et al. Radiofrequency ablation of hepatic metastases from colorectal cancer: are newer generation probes better? Am. Surg., 2006; 72: 875–879.

2. Aloia, T. A., Vauthey, J. N., Loyer, E. M., et al. Solitary colorectal liver metastasis: resection determines outcome. Arch. Surg., 2006; 141: 460–467.

3. Giorgio, A., Tarantino, L., Mariniello., N., et al. Ultrasonography-guided percutaneous ethanol injection in large an/or multiple liver metastasis. Radiol. Med. (Torino), 1998; 96: 238.

4. Giovannini, M., Seitz, J. F. Ultrasound-guided percutaneous alcohol injection of small liver metastases. Results in 40 patients. Cancer, 1994; 73: 294.

5. Goldberg, S. N., Hahn, P. F., Tanabe, K. K., et al. Percutaneous radiofrequency tissue ablation: does perfusion-mediated tissue cooling limit coagulation necrosis? J. Vasc. Interv. Radiol., 1998; 9: 101.

6. Kornprat, P., Jarnagin, W. R., DeMatteo, R. P., et al. Role of intraoperative thermoablation combined with resection in the treatment of hepatic metastasis from colorectal cancer. Arch. Surg., 2007; 142: 1087.

7. Oshowo, A., Gillams, A., Harrison, E., et al. Comparison of resection and radiofrequency ablation for treatment of solitary colorectal liver metastases. Br. J. Surg., 2003; 90: 1240–1243.

8. Siperstein, A. E., Berber, E., Ballem, N., Parikh, R. T. Survival after radiofrequency ablation of colorectal liver metastases: 10-year experience. Ann. Surg., 2007; 246: 559.

9. Vysloužil, K., et al. Radiofrequenzablation von kolorektalen Lebermetastasen. Zentralbl. Chir., 2008; 133:1–4.

Labels
Surgery Orthopaedics Trauma surgery
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#