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Tumorous Stem Cells – A Novel View in Oncology?


Authors: V. Liška 1;  V. Třeška 1;  M. Korabečná 2
Authors‘ workplace: Chirurgická klinika, FN Plzeň-Lochotín, LF UK v Plzni, přednosta: prof. MUDr. V. Třeška, DrSc. 1;  Biologický ústav, LF UK Plzeň, přednosta: doc. RNDr. J. Reischig, CSc. 2
Published in: Rozhl. Chir., 2007, roč. 86, č. 10, s. 548-552.
Category: Monothematic special - Original

Overview

Authors present contemporary knowledges, arguments and hypothesis about cancer STEM cells and their relations to current concepts of oncology and surgical oncology. The aim is to introduce new view of carcinogenesis and origin of metastatical process as a diseas of STEM cells to general surgical public that deal with surgical oncology and is confronted with new trends in modern oncological pharmacology. The presented theory of tumour origin by cancer STEM cells is confronted critically with all current theories.

Key words:
cancer STEM cell – embryonal STEM cell – adult STEM cell – cancerogenesis – metastatical process – surgical oncology


Sources

1. Reya, Morrison, S. J., Clarke, M. F., Weissman, I. L. Stem cells, cancer, and cancer stem cells. Nature, 2001, 414: 105–111.

2. Takano, T. Fetal cell carcinogenesis of the thyroid: theory and practice. ., 2007, 17: 233–240.

3. Woodward, W, A., Chen, M. S., Behbod, F., Rosen, J. M. J. On mammary stem cells. Cell Sci., 2005, 118: 3585–3594.

4. Soltysova, A., Altanerova, V., Altaner, C. Cancer stem cells. Neoplasma, 2005, 52: 435–440.

5. Haura, E. B. Is repetitive wounding and bone marrow-derived stem cell mediated-repair an etiology of lung cancer development and dissemination? Med. Hypothese, 2006, 67: 951–956.

6. Jain, R. K., Duda, D. G. Role of bone marrow-derived cells in tumor angiogenesis and treatment. Cancer Cell, 2003, 3: 515–516.

7. Wu, X. Z., Yu, X. H. Bone marrow cells: The source of hepatocellular carcinoma? Med. Hypothese, 2007, 69: 36–42.

8. Rizvi, A.Z., Swain, J. R., Davies, P. S., Bailey, A. S., Decker, A. D., Willenbring, H., Grompe, M., Fleming, W. H., Wong, M. H. Bone marrow-derived cells fuse with normal and transformed intestinal stem cells. Proc. Natl. Acad. Sci. U S A, 2006, 103: 6321–6325.

9. Duesberg, P., Li, R., Fabarius, A., Hehlmann, R. The chromosomal basis of cancer. Cellular Oncology, 2005, 27: 293–318.

10. Liu, C., Chen, Z., Zhang, T., Lu, Y. Multiple tumor types may originate from bone marrow-derived cells. Neoplasia, 2006, 8: 716–724.

11. Hattori, K., Heissig, B., Wu, Y., Dias, S., Tejada, R., Ferris, B., Hicklin, D.J., Zhu, Z., Bohlen, P., Witte, L., Hendrikx, J., Hackett, N.R., Crystal, R.G., Moore, M.A., Werb, Z., Lyden, D., Rafii, S. Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment. Nat. Med., 2002, 8:8 41–849.

12. Wu, X. Z., Chen, D., Xie, G. R. Bone marrow-derived cells: roles in solid tumor. Neoplasma, 2007,54: 1–6.

13. Rubio, D., Garcia-Castro, J., Martin, M. C., de la Fuente, R., Cigudosa, J. C., Lloyd, A. C., Bernad, A. Spontaneous human adult stem cell transformation.Cancer Res, 2005, 65: 3035–3039.

14. Sagar, J., Chaib, B., Sales, K., Winslet, M., Seifalian, A. Role of stem cells in cancer therapy and cancer stem cells: a review. Cancer Cell Int, 2007, 7: 9.

15. Kaplan, R. N., Psaila, B., Lyden, D. Bone marrow cells in the ‘pre-metastatic niche’: within bone and beyond. Cancer Metastasis Rev., 2006, 25: 521–529.

16. Kaplan, R. N., Psaila, B., Lyden, D. Niche-to-niche migration of bone-marrow-derived cells. Trends Mol Med, 2007, 13: 72–81.

17. Kaplan, R. N., Riba, R. D., Zacharoulis, S., Bramley, A. H., Vincent, L., Costa, C., MacDonald, D. D., Jin, D. K., Shido, K., Kerns, S. A., Zhu, Z., Hicklin, D., Wu, Y., Port, J. L., Altorki, N., Port, E. R., Ruggero, D., Shmelkov, S. V., Jensen, K. K., Rafii, S., Lyden, D. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature, 2005, 438: 820-827.

18. Oppenheimer, S. B. Cellular basis of cancer metastasis: A review of fundamentals and new advances. Acta Histochem., 2006,108: 327–334.

19. Theise, N. D., Yao, J. L., Harada, K., Hytiroglou, P., Portmann, B., Thung, S. N., Tsui, W., Ohta, H., Nakanuma, Y. Hepatic ‘stem cell’ malignancies in adults: four cases. Histopathology, 2003, 43: 263–271.

20. Ma, S., Chan, K. W., Hu, L., Lee, T. K., Wo, J. Y., Ng, I. O., Zheng, B. J., Guan, X. Y. Identification and characterization of tumorigenic liver cancer stem/progenitor cells. Gastroenterology, 2007, 132: 2542–2556.

21. Baker, K. S., DeFor, T. E., Burns, L. J., Ramsay, N. K., Neglia, J. P., Robison, L. L. New malignancies after blood or marrow stem-cell transplantation in children and adults: incidence and risk factors. J. Clin. Oncol., 2003, 21:1352–1358.

22. Bhatia, S., Louie, A. D., Bhatia, R., O‘Donnell, M. R., Fung, H., Kashyap, A., Krishnan, A., Molina, A., Nademanee, A., Niland, J. C., Parker, P. A., Snyder, D. S., Spielberger, R., Stein, A., Forman, S. J. Solid cancers after bone marrow transplantation. J. Clin. Oncol., 2001, 19: 464–471.

23. Pardal, R., Clarke, M. F., Morrison, S. J. Applying the principles of stem-cell biology to cancer. Nat. Rev. Cancer, 2003, 3: 895–902.

24. Duelli, D., Lazebnik, Y. Cell fusion: a hidden enemy? Cancer Cell, 2003, 3: 445–448.

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