Cholesterol measurement and current guidelines
Authors:
Vladimír Soška
Authors‘ workplace:
Oddělení klinické biochemie, Fakultní nemocnice u sv. Anny v Brně
Published in:
Vnitř Lék 2022; 68(1): 54-57
Category:
Review Articles
Overview
The concentration of total cholesterol has so far been part of the SCORE tables for estimating the risk of cardiovascular events; in the new SCORE2 tables, it has already been replaced by non-HDL-cholesterol. Total cholesterol continues to serve as a guide for the presence of dyslipoproteinemia and is necessary for the calculation of LDL-cholesterol and non-HDL-cholesterol. The importance of HDL-cholesterol as a separate risk factor is already limited, but it is necessary for the calculation of non-HDL-cholesterol and LDL-cholesterol. LDL-cholesterol remains an essential indicator of risk, it is needed for decision making and control of hypolipidemic therapy. Non HDL-cholesterol can be used as a therapy target instead of LDL-cholesterol. Triglycerides remain necessary for residual risk assessment, for the calculation of LDL-cholesterol and for the diagnosis of certain types of dyslipoproteinemias.
Keywords:
triglycerides – atherosclerotic cardiovascular diseases – HDL‑ cholesterol – LDL‑ cholesterol – non HDL‑ cholesterol – total cholesterol
Sources
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Internal Medicine
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