Authors: J. Smetana; M. Vacková; R. Chlíbek Authors‘ workplace: Univerzita obrany, Katedra epidemiologie Fakulty vojenského zdravotnictví v Hradci Králové Published in: Epidemiol. Mikrobiol. Imunol. 56, 2007, č. 3, s. 112-118
The group of prion diseases includes many diagnoses which have been long known. Nevertheless, the general awareness of these diseases increased substantially with the outbreaks of bovine spongiform encephalopathy (BSE) and the emergence of a new variant of Creutzfeldt-Jakob disease (nvCJD) at the close of the XXth century. Although major advances have been made in this field, further research is required to better understand these diseases. Many questions related e.g. to the accurate definition of the causative agent, pathogenesis, diagnosis and treatment still need to be addressed. The aim of this article is to present the latest knowledge of the etiology and epidemiology of these diseases with a focus on BSE and nvCJD, including measures taken for their control.
Key words: prion diseases – bovine spongiform encephalopathy – Creutzfeldt-Jakob disease – epidemiology.
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