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Mezenchymální kožní tumory – Nové jednotky v 5. edici WHO klasifikaci nádorů kůže

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Authors: Michael Michal
Authors‘ workplace: Bioptická laboratoř, s. r. o., Plzeň ;  Šiklův ústav patologie LF UK a FN Plzeň
Published in: Čes.-slov. Patol., 60, 2024, No. 1, p. 49-58
Category: Reviews Article

Overview

V roce 2023 vydávaná 5. edice WHO klasifikace nádorů kůže doznala v sekci mezenchymálních nádorů několika změn, přičemž mezi nejvýznamnější, jako již tradičně, patří zařazení nově identifikovaných nádorových jednotek, kterými se tento přehledový článek bude zabývat především. Konkrétně se jedná o tři nové kožní mezenchymální tumory s melanocytární diferenciací a rearanžemi genů CRTC1::TRIM11, ACTIN::MITF a MITF::CREM. Dále byly nově zařazeny EWSR1::SMAD3- rearanžované fibroblastické tumory, superficiální CD34 pozitivní fibroblastické tumory a NTRK-rearanžované vřetenobuněčné neoplazie. Z dalších změn budou krátce zmíněny pouze ty nejvýznamnější.

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Labels
Anatomical pathology Forensic medical examiner Toxicology
Histopatologická diagnostika nádorových onemocnění kůže
Mám štěstí na skvělé spolupracovníky
MONITOR aneb nemělo by vám uniknout, že...
Histopatologická diagnostika kožních melanocytárních lézí
Klinické, morfologické a molekulární vlastnosti Spitzoidních nádorů
Změny v bioptické diagnostice nádorů štítné žlázy v 5. vydání WHO klasifikace nádorů endokrinních orgánů
Změny v hlášení tyreoidálních cytologií ve 3. vydání Bethesda systému
Nádory příštítných tělísek v 5. vydání WHO klasifikace nádorů endokrinních orgánů
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