New perspectives in patients with prostate cancer before and after kidney  transplantation

Overview

Over recent decades, there has been a signifi cant increase in patients treated for end‑stage renal disease diagnosed with prostate cancer before kidney transplantation, as well as an increase in kidney transplant recipients diagnosed with pros tate cancer . Pre‑transplant screening, the aging population, and extended survival post‑transplant play a role . New insights lead to adjustments in some diagnostic and therapeutic procedures in this patient group, yet clear recommended guide lines remain absent . Also, patients with low‑risk prostate cancer in active surveillance or after curative therapy are no longer required to wait before being listed for transplantation . Special at tention is given to the role of immunosuppressive therapy, which is essential for the function of the transplanted kidney but may also influence the risk and course of oncological disease . Modifying or reducing immunosuppression, as suggested by current literature, may be a reasonable step in some cases but requires careful consideration in the context of the individual patient . Patients who have undergone kidney transplantation and are diagnosed with prostate cancer achieve similar treatment outcomes as patients with no end‑stage renal disease . In the text, we summarize current knowledge regarding epidemiology, treatment options, and challenges faced by medicine in pa tients with prostate cancer before and after kidney transplantation, including their differences from the general population

Keywords:

Prostate cancer, kidney transplantation, waiting list .