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Utilization of an extra-anatomic stent (EAS) in the management of patients with advanced malignant disease


Authors: David Němec;  Jan Krhut;  David Míka;  Ondřej Havránek
Authors‘ workplace: Urologické oddělení FN, Ostrava
Published in: Ces Urol 2012; 16(4): 241-246
Category: Original article

Overview

Aim:
Ureteral obstruction is a frequent complication in patients with malignant diseases. The most frequently used solutions are a ureteral stent, nephrostomy or open surgical intervention. An extra-anatomic stent (EAS) represent an alternative method for urinary diversion in patients with advanced malignancy and short life expectancy. The aim of this paper is to verify the efficacy of using an EAS for urinary diversion and to evaluate the quality of life (QoL) following the procedure.

Methods:
The study included 11 patients (8 men and 3 women), with a mean age of 64.5 years (38–80 years). Five patients with advanced bladder carcinoma, three patients suffered from locally advanced prostate cancer, one patient with locally advanced cervical cancer and two patients with generalized colorectal cancer. In 9 cases, patients received diversion using a urostomy bag, in 2 cases EAS was used as a bilateral nephrovesical bypass. QoL was evaluated using the King’s Health Questionnaire before and 4 weeks after treatment. The results were evaluated using the Wilcoxon test with a significance level of 0.05.

Results:
During a mean follow-up period of 40 weeks (8–55 weeks), QoL after the EAS insertion increased significantly for all parameters. Hydronephrosis was resolved by EAS insertion in 10 cases and improved in one patient. Preoperative serum creatinine level (186,6 ± 64,67 μmol/l) decreased significantly postoperatively (106 ± 24,49 μmol/l).

Conclusion:
EAS represents a promising treatment alternative for dealing with ureteral obstruction in the terminal stage of malignant diseases. The procedure is not difficult and has good functional results, with a significant increase in the quality of life for patients.

Key words:
extra-anatomic stent, ureteral obstruction, nephrostomy, Quality of Life.


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Labels
Paediatric urologist Nephrology Urology
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