#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Hemosiderotic Dermatofibroma with Atrophic Features. Case Report


Authors: P. Ďuríková 1;  V. Bartoš 2
Authors‘ workplace: Dermatovenerologická klinika, Univerzita Komenského, Univerzitná nemocnica Bratislava 1;  Martinské bioptické centrum, s. r. o., Martin 2
Published in: Čes-slov Derm, 100, 2025, No. 3, p. 133-136
Category: Case Reports

Overview

Hemosiderotic dermatofibroma represents a rare subtype of dermatofibroma, characterized by the presence of numerous small vessels, siderophages, and hemosiderin deposits, which can have a wider variety of clinical manifestations. Atrophic dermatofibroma, another rare variant, presents as an atrophic plaque of varying colors. We report a case of a 27-year-old woman with a slow-growing, atrophic bluish-brown plaque on her right lower leg that developed after minor trauma. Histopathological examination of the biopsy revealed an intradermal tumor with hemosiderin deposits, histiocytes, and giant Touton cells.

The diagnosis of hemosiderotic dermatofibroma was confirmed by immunohistochemical staining, demonstrating positivity for Factor XIIIa and negativity for CD34. Due to the progressive nature of the lesion, a complete surgical excision was recommended, but the patient refused. This case illustrates the rare coexistence of hemosiderotic and atrophic features in a dermatofibroma, highlighting the importance of a comprehensive diagnostic approach.

Keywords:

case report – dermatofibroma – hemosiderotic dermatofibroma – atrophic dermatofibroma – fibrous histiocytoma


Sources
  1. CURCÓ, N., PAGEROLS, X., GARCÍA, M. et al. Atrophic dermatofibroma accompanied by aneurysmatic characteristics. J Eur Acad Dermatol Venereol, 2006, 20(3), p. 331–333.
  2. GAGNIER, J. J., KIENLE, G., ALTMAN, D. G. et al. The CARE Guidelines: Consensus-based Clinical Case Reporting Guideline Development. Glob Adv Health Med, 2013, 2(5), p. 38–43.
  3. GENC, Y., AKAY, B. N., OKCU HEPER, A. et al. Dermatopathological characteristics of dermatofibromas from dermatoscopic clues. Int J Dermatol, 2019, 59(1), p. 66–75.
  4. GUTIERREZ, N., CALAME, A., ERICKSON, C. et al. Atrophic Dermatofibroma: A Unique Dermatofibroma Variant. Cureus, 2021, 13(4), p. e14570.
  5. LAGZIEL, T., SYLVESTER, S., HULTMAN, C. S. et al. Hemosiderotic Dermatofibroma: A Rare and Atypical Variant Capable of Clinically Resembling Melanoma. Cureus, 2020, 12(1), p. e6736.
  6. LI, C., ALLEN, H., LOXAS, M. et al. Hemosiderotic dermatofibroma mimicking melanoma: A case report and review of the literature. Clin Case Rep, 2021, 9(3), p. 1387–1392.
  7. MENZIES, S. W., MOLONEY, F. J., BYTH, K. et al. Dermoscopic evaluation of nodular melanoma. JAMA Dermatol, 2013, 149(6), p. 699–709.
  8. SHIN, J. W., PARK, H. S., KIM, B. K. et al. Aneurysmal benign fibrous histiocytoma with atrophic features. Ann Dermatol, 2009, 21(1), p. 42–45.
  9. BAI J., LIU B., LIU T. et al. Atrophic Pigmented Dermatofibrosarcoma Protuberans: A Case Report and Literature Review. Front Oncol, 2021, 11, p. 669754.
  10. WEST, K. L., CARDONA, D. M., SU, Z. et al. Immunohistochemical markers in fibrohistiocytic lesions: factor XIIIa, CD34, S-100 and p75. Am J Dermatopathol, 2014, 36(5), p. 414–419.
  11. ZABALLOS, P., ÁLVAREZ-SALAFRANCA, M., LLAMBRICH, À. et al. Dermoscopy of haemosiderotic/aneurysmal dermatofibroma: A morphological study of 110 cases. J Eur Acad Dermatol Venereol, 2023, 37(2), p. 317–327.

Poďakovanie

Tento prípad bol prezentovaný na konferencii „Dermatológia pre prax“ dňa 9. novembra 2024 v Tatranskej Lomnici. Na jazykovú úpravu bol použitý nástroj ChatGPT-4, pričom všetky konečné rozhodnutia uskutočnili autori. Na tento rukopis neboli poskytnuté žiadne finančné prostriedky.

Konflikt záujmov

Autory v súvislosti s témou práce za posledných 12 mesiacov nespolupracovali so žiadnou farmaceutickou spoločnosťou.

Do redakce došlo dne 15. 1. 2025.
Adresa pro korespondenci: MUDr. Paula Ďuríková
Dermatovenerologická klinika, Univerzita Komenského
Univerzitná nemocnica Bratislava
Mickiewiczova 13
813 69 Bratislava Slovenská republika
e-mail:
durikova16@uniba.sk

Labels
Dermatology & STDs Paediatric dermatology & STDs
Topics Journals
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#