What is the Prevalence of Atopic Dermatitis in the Czech Republic?
Authors:
N. Benáková 1,2; J. Jarkovský 3,4; A. Zouharová 3
Authors‘ workplace:
Dermatoalergologická ordinace Immunoflow Praha, vedoucí lékař prim. MUDr. Martin Fuchs
1; Dermatovenerologická klinika 1. LF UK Praha, přednosta prof. MUDr. Jiří Štork, CSc.
2; Ústav zdravotnických informací a statistiky ČR, ředitel prof. RNDr. Ladislav Dušek, Ph. D.
3; Institut biostatistiky a analýz, LF MU Praha, vedoucí prof. RNDr. Ladislav Dušek, Ph. D.
4
Published in:
Čes-slov Derm, 98, 2023, No. 1, p. 15-24
Category:
Pharmacologyand Therapy, Clinical Trials
Overview
This article presents a qualified estimate of the prevalence of atopic dermatitis in Czech Republic. This search included all citizens who visited a physician in 2010–2021 and who were reported with a diagnosis of atopic dermatitis to national registry for health services (NRHZS). The overall prevalence in this period ranged from 2.0–2.2%, of which the relative prevalence in children fluctuated between 4.7–5.8 % and the relative prevalence in adults was 1.4–1.5%. The real prevalence will probably be higher, and methodologically, persons with mild atopic dermatitis, especially children, may be missed. Confusion with other eczema-dermatitis may also be a potential cause of the lower prevalence data for atopic dermatitis, that is why their prevalence was also monitored, but it was low. Prevalence was also followed in five age subgroups and showed an increase in adulthood, where the cause is likely to be the first manifestation of atopic dermatitis in adulthood ('adult-onset') rather than persistence from childhood. The proportion of severe atopic dermatitis in the population of patients with atopic dermatitis in the Czech Republic (10.4%) is in line with international data. The observed low participation of physicians other than dermatologists in the care of patients with atopic dermatitis is probably due to undereporting, but it remains to be investigated.
Keywords:
prevalence of atopic dermatitis in Czech Republic in 2010–2021 – adult-onset atopic dermatitis – severity – medical care according to specialties
Sources
1. ABUBARA, K., YE, M., MCCULLOCH, CH. et al. Clinical onset of atopic eczema: Results from 2 nationally representative British birth cohorts followed through midlife. J. Allergy Clin. Immunol., 2019, 144, p. 710–719.
2. BANNISTER, M.J., FREEMAN, S. Adult onset atopic dermatitis. Australas J. Dermatol., 2000, 41(4), p. 225–228.
3. BARBAROT, S., AUZIERE, S., GADKARI, A. et al. Epidemiology of atopic dermatitis in adults: Results of international survey. Allergy, 2018,73, p. 1284–1293.
4. BIEBER, T. Atopic dermatitis. N. Eng. J. Med., 2008, 358, p. 1483–1494.
5. BIEBER, T. Clinical phenotypes and endophenotypes of atopic dermatitis: where are we and where should we go. J. Allergy Clin. Immunol., 2017, 139 (4S), p. S58–S64.
6. BOK, Y. P. Natural history and risk factors of atopic dermatitis in children. Allergy Asthma Immunol. Res., 2015, 7, p. 101–105.
7. FUXENCH, Z.C.C., BLOCK, J. K., BOGUNIEWICZ, M. et al. Atopic Dermatitis in America Study: A cross-sectional study examining the prevalence and disease burden of atopic dermatitis in the US adult population. J. Invest. Dermatol., 2019,139, p. 583–590.
8. GARMHAUSEN, D., HAGEMANN, T., BIEBER, T. et al. Characterization of different courses of atopic dermatitis in adolescent and adult patients. Allergy, 2013, 68, p. 498–506.
9. HAGENSTRÖM, K., SAUER, K., MOHR, N. et al. Prevalence and Medications of Atopic Dermatitis in Germany: Claims Data Analysis. Clin. Epidemiol., 2021,13, p. 593–602.
10. HAJAR, T., SIMPSON, E. L. The rise in atopic dermatitis in young children: what is the explanation? JAMA Netw Open., 2018, 1(7), p. e184205.
11. HARROP, J., CHINN, S., VERLATO, G. et al. Eczema, atopy and allergen exposure in adults: a population-based study. Clin Exp Allergy., 2007, 37(4), p. 526–535.
12. HUA, T., SILVERBERG, J. I. Atopic dermatitis in US adults: epidemiology, association with marrital status and atopy. Ann. Allergy Asthma Immunol., 2018, 121, p. 622–624.
13. KAUFMAN, B. P., GUTTMANN-YASKY, E., ALEXIS, A. F. Atopic dermatitis in diverse racial and ethnic groups – variations in epidemiology, genetics, clinical presentations and treatments. Exp. Dermatol., 2018, 27, p. 340–357.
14. KIM, J. P., CHAO, L. X., SIMPSON, E. L., SILVERBERG, J. I. Persistence of atopic dermatitis (D): a systematic review and meta-analysis. J. Am. Acad. Dermatol, 2016, 75, p. 681–687.
15. LEE, H. H., PATEL, K. R., SINGAM, V. et al. A systematic review and meta-analysis of the prevalence and phenotype of adult-onset atopic dermatitis. J. Am. Acad. Dermatol., 2019, 80, p. 1526–1532.
16. LEE, J. Y. KIM, J., AHN, K. Time trends in the prevalence of atopic dermatitis in Korean children according to age. Allergy Asthma Immunol. Res., 2022, 14(1), p. 123–130.
17. MORTZ, C. G., ANDERSEN, K. E., DELLGREN, C., BARINGTON, T., BINDSLEV-JENSEN, C. Atopic dermatitis from adolescence to adulthood in the TOACS cohort: prevalence, persistence and comorbidities. Allergy, 2015, 70, p. 836–845.
18. NIJS DE, S. B., VENEKAMP, L. N., BEL, E. H. Adult-onset asthma: is it really different? Eur. Respir. Review., 2013, 22, p. 44–52.
19. RODUIT, C. et al. Phenotypes of atopic dermatitis depending on the timing of onset and progression in childhood. JAMA Pediatr., 2017, 171(1), p. 655–662.
20. SANCLEMENTE, G., HERNANDEZ, M., CHAPARRO, D. et al. Epidemiologic features and burden of atopic dermatitis in adolescent and adult patients: A cross sectional muticenter study. World Allergy Organ., 2021,14(12), p. 100611.
21. SILVERBERG, J. I. Public health burden and epidemiology of atopic dermatitis. Dermatol. Clin., 2017, 35, p. 283–289.
22. SILVERBERG, J. I. Atopic dermatitis in adults. Med. Clin. N. Am., 2020, 104, p. 157–176.
23. SON, J. H., CHUNG, B. Y., KIM, H. O. et al. Clinical features of atopic dermatitis in adults are different according to onset. J. Korean Med. Sci., 2017, 32, p. 1360–1366.
24. ŠTORK, J. Dermatovenerologie. 2.vyd. Praha: Galén, 2013, p. 162. ISBN 978-80-7262-898-8.
25. VOLKE, A., TOOMPERE, K., LAISAAR. K. et al. 12-month prevalence of atopic dermatitis in resource- rich countries: a systematic review and meta-analysis. Sci. Rep., 2022, 12(1), p. 15125.
26. ZIETZE, H. A., CABRAL, C., THEOBALD, K. et al. Epidemiology and treatment of adult patients with atopic dermatitis: Analysis of longitudinal data of the statutory health insurance scheme. Hautarzt, 2021, 72(11), p. 963–974.
Labels
Dermatology & STDs Paediatric dermatology & STDsArticle was published in
Czech-Slovak Dermatology
2023 Issue 1
Most read in this issue
- What is the Prevalence of Atopic Dermatitis in the Czech Republic?
- Hapteny pro epikutánní testování jsou k dispozici
- Cutaneous Amyloidosis. A Review
- Dermatoscopy in „Atypical“ Locations: Flat Pigmented Lesions on the Acral Parts of the Limbs