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Use of Antimalarials in Dermatology


Authors: R. Litvik 1,2
Authors‘ workplace: Kožní oddělení Fakultní nemocnice Ostrava přednosta prim. MUDr. Yvetta Vantuchová, Ph. D. 1;  Centrum plastické chirurgie a chirurgie ruky Fakultní nemocnice Ostrava přednosta prim. MUDr. Martin Paciorek 2
Published in: Čes-slov Derm, 92, 2017, No. 2, p. 55-61
Category: Reviews (Continuing Medical Education)

Overview

The author gives an overview of current knowledge regarding the use of antimalarials in dermatology. Common antimalarial drugs include chloroquine, hydroxychloroquine and quinacrine. Antimalarials, mainly chloroquine and hydroxychloroquine, have been used in dermatology for more than 50 years in the treament of cutaneous lupus erythematosus. Mechanism of their action is broad, currently they are known as lysosomotropic drugs. Treatment with antimalarials is safe, ocular toxicity should be mainly considered.

Key words:
antimalarial – chloroquine – hydroxychloroquine – lupus erythematosus


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Dermatology & STDs Paediatric dermatology & STDs
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